期刊文献+

睡眠过程中交感和副交感拮抗活动的初步分析 被引量:1

Analysis the antagonistic interaction of sympathetic and parasympathetic nerve function during sleep
下载PDF
导出
摘要 目的探讨睡眠过程中交感和副交感神经功能的拮抗关系。方法对10名健康年轻大学生(男性7名,女性3名,年龄19-23岁)使用Holter,L,电图仪进行连续心电监测,将所获R-R间隔的时间序列资料以10分钟为一个单位进行分隔,利用粗视化频谱分析技术(Coarse Graining Spectral Analysis,CGSA)分析SNS和PNS拮抗活动的趋势。结果进入睡眠期后SNS活动明显下降,而PNS活动明显增强,觉醒后交替。且每个单位的PNS和SNS值呈反比例函数关系。结论睡眠过程中交感和副交感神经功能存在相互拮抗的关系,此消彼长。 Objective To discuss the antagonistic interaction of sympathetic and parasympathetic nerve function during sleep. Methods Ten healthy university students(male 7,female3,aged between 19.23) were enrolled in this study. Hoher ECG was recorded for each subject. The RR intervals were continuously divided by 10 minutes,and then analyzed by coarse graining spectral analysis (CGSA). Results After entering the sleep period,the SNS activity decreased significantly, while the PNS activity increased and they alternated after wake up. At the same time, each unit of the PNS(parasympathetic nerve system) and SNS (sympathetic nerve system) values showed a inverse proportion function relationship. Conclusions The PNS and SNS have antagonistic interaction during sleep and they shift according to the stages of sleep.
出处 《中国中西医结合耳鼻咽喉科杂志》 2015年第5期368-371,共4页 Chinese Journal of Otorhinolaryngology in Integrative Medicine
基金 江苏省卫生厅科教兴卫开放课题(XK19200901) 南京医科大学第一附属医院创新团队基金(IRT-16) 教育部留学回国人员科研启动基金(20101174)
关键词 阻塞性睡眠呼吸暂停综合征 交感/副交感神经 粗视化频谱分析 拮抗 Obstructive sleep apnea Sympathet ..iparasympathetic nervous CGSA Antagonistic interaction
  • 相关文献

参考文献19

  • 1徐允良,陈建良,殷敏,等.睡眠过程中副交感神经功能粗视化频谱分析的初步探讨.中国中西医结合耳鼻咽喉科杂志.2010,18:312—315.
  • 2Yin M, Nakayama M, Miyazaki S, et al. How much influence does inspiration have on pulse transit time in sleep apnea [J]. Otolaryngol Head Neck Surg, 2008, 138 (5): 619-625.
  • 3Woodson BT, Brusky LT, Saurajen A, et al. Association of autonomic dysfunction and mild obstructive sleep apnea [J]. Otolaryngol Head Neck Surg, 2004, 130(6): 643-648.
  • 4Smith R P, Veale D, Pepin J L, et al. Obstructive sleep apnoea and the autonomic nervous system [J]. Sleep Med Rev, 1998, 2(2): 69-92.
  • 5Zamarron C, Gude F, Barcala J, et al. Utility of oxygen saturation and heart rate spectral analysis obtained from pulse oximetric recordings in the diagnosis of sleep apnea syndrome[J]. Chest, 2003, 123(5): 1567-1576.
  • 6Jurysta F, Lanquart J P, van de Borne P, et al. The link between cardiac autonomic activity and sleep delta power is altered in men with sleep apnea-hypopnea syndrome[J]. Am J Physiol Regul Integr Comp Physiol, 2006, 291 (4): R1165-R1171.
  • 7Tabata R, Yin M, Nakayama M, et al. A preliminary study on the influence of obstructive sleep apnea upon cumulative parasympathetic system activity [J]. Aufis Nasus Larynx, 2008, 35(2): 242-246.
  • 8Yamamoto Y, Hughson R L. Coarse-graining spectral analysis: new method for studying heart rate variability[J]. J Appl Physiol (1985), 1991, 71(3): 1143-1150.
  • 9久次米真吾,野呂員人,森山明義,熊谷賢太,酒井毅,沼田綾香,中江武志,手塚尚紀,坂田隆夫,杉薫.発作性心房細動時の自律神経解析の試みーMemcalcを用いて一.心電図27:518,2007.
  • 10丸山徹.心拍変動の線形解析.自律神経44:66-70, 2007.

二级参考文献28

  • 1吴睿,张希龙.经鼻持续气道正压通气对阻塞性睡眠呼吸暂停低通气患者血清脂联素和血压的影响[J].南京医科大学学报(自然科学版),2007,27(1):36-38. 被引量:13
  • 2黎燕群,张希龙.持续正压通气治疗对阻塞性睡眠呼吸暂停综合征患者难治性高血压的影响[J].南京医科大学学报院自然科学版,2008,28(2):210-214.
  • 3Arzt M,Young T,Finn L,et al. Sleepiness and sleep inpatients with both systolic heart failure and obstructivesleep apnea [J]. Arch Intern Med,2006,166(16):1716-1722.
  • 4Park DH,Shin CJ,Hong SC,et al. Correlation between theseverity of obstructive sleep apnea and heart rate variabili-ty indices[J]. J Korean Med Sci,2008,23(2) :226-231.
  • 5徐允良,陈建良,殷敏,等.睡眠过程中副交感神经功能粗视化频谱分析的初步探讨[J].中国中西医结合耳鼻咽喉科杂志,2010,18(6) :312-315.
  • 6Scholz UJ,Bianchi AM,Cerutti S,et al. Vegetative Back-ground of Sleep : Spectral Analysis of the Heart RateVariability[J]. Physiol Behav,1997,62(5): 1037-1043.
  • 7Trinder J,Kleiman J,Carrington M,et al. Autonomic ac-tivity during human sleep as a function of time and sleepstage[J]. J Sleep Res,2001,10(4):253-264.
  • 8Zhu K,Chemla D,Roisman G,et al. Overnight heart ratevariability in patients with obstructive sleep apnea : Atime and frequency domain study [J]. Clin Exp Pharma-col Physiol,2012,39(11): 901-908.
  • 9Aydin M,Altin R,Ozeren A,et al. Cardiac AutonomicActivity in Obstructive Sleep Apnea Time-Dependent andSpectral Analysis of Heart Rate Variability Using 24-Hour Holter Electrocardiograms [J]. Tex Heart Inst J,2004,31(2):132-136.
  • 10Tabata R,Yin M,Nakayama M,at al. A preliminary studyon the influence of obstructive sleep apnea upon cumula-tive parasympathetic system activity[J]. Auris Nasus Lar-ynx,2008,35(2):242-246.

共引文献8

同被引文献20

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部