摘要
目的比较超声刀手术与传统手术治疗甲状腺疾病患者应激反应差异。方法将116例甲状腺疾病患者随机分为超声刀组56例和电刀组60例。电刀组患者给予传统手术方法治疗,超声刀组给予超声刀手术治疗。应用SPSS 18.0软件包进行数据处理,手术相关指标和应激反应相关指标等计量资料呈正态分布,用（±s）表示,两组间比较采用成组设计资料的t检验;并发症等计数资料采用χ~2检验。P〈0.05为差异具有统计学意义。结果超声刀组患者手术时间为（62.6±12.4）min、切口长度为（5.1±1.0）cm、出血量为（29.8±7.8）ml和引流量为（31.5±10.5）ml均显著低于电刀组（t=14.76,23.46,9.06,11.12,P〈0.01）差异具有统计学意义。超声刀组患者术后白细胞计数为（9.9±1.9）×109/L、粒细胞百分比为（76.2±6.1）%、C反应蛋白水平为（83.8±13.8）mg/L、空腹血糖为（6.1±1.5）mmol/L,显著低于电刀组（t=10.11,6.79,20.87,2.62,P〈0.01）差异具有统计学意义。超声刀组患者术后并发症发生率为10.7%（6/56）,显著低于电刀组的26.7%（16/60）,两组比较差异有统计学意义,χ~2=4.80,P〈0.05。结论超声刀手术应用于甲状腺疾病的治疗临床效果更优、患者应激反应更小,具有临床应用价值。
Objective To study the clinical outcome of stress response between harmonic scalpel and traditional method in open thyroid surgery. Methods A total of 116 patients undergoing open thyroid surgery were randomly divided into a harmonic scalpel group（ 56 patients） and an electrotome group（ 60patients）. Patients in the electrotome group were treated by open thyroid surgery and those in the harmonic scalpel group by harmonic scalpel open thyroid surgery. SPSS 18. 0 software was employed to analyze clinical data. Operative indexes and stress response indexes were normally distributed. Accumulated data including complications were analyzed by the Chi- square test. P〈0. 05 was considered statistically significant.Results The operative time was（ 62. 6 ± 12. 4） min,incision length was（ 5. 1 ± 1. 0） cm,blood loss was（ 29. 8 ± 7. 8） ml,and drainage volume was（ 31. 5 ± 10. 5） ml in the harmonic scalpel group,all of which were significantly less than those in the electrotome group（ t = 14. 76,23. 46,9. 06,11. 12 respectively,P〈0. 01）. The white blood cell count,neutrophil percentage（ 9. 9 ± 1. 9） × 109/ L,neutrophil percentage（ 76. 2 ± 6. 1） %,C- reactive protein（ 83. 8 ± 13. 8） mg/L and blood glucose（ 6. 1 ± 1. 5） mmol/L in the harmonic scalpel group were significantly lower than those in the electrotome group（ t = 10. 11,6. 79,20. 87,2. 62 respectively,P〈0. 01）. The rate of complications in the harmonic scalpel group was 10. 7%（ 6 /56）,which was significantly lower than 26. 7%（ 16 /60） in the electrotome group（ χ~2= 4. 80,P〈0. 05）. Conclusion armonic scalpel used in open thyroid surgery has a better clinical effect and less stress response,It is worth using clinically.
出处
《中华普外科手术学杂志（电子版）》
2015年第6期53-55,共3页
Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
