摘要
目的探讨血清促甲状腺激素(TSH)水平与甲状腺乳头状癌颈侧区淋巴结转移的关系。方法回顾性分析2010年1月至2014年12月收治的127例甲状腺乳头状癌患者和50例甲状腺良性结节患者临床资料。应用SPSS 20.0软件包进行数据处理,患者的病理资料、TSH水平等以(±s)表示,采用t检验。P<0.05为差异具有统计学意义。结果甲状腺癌患者的TSH为(2.4±0.7)μIU/ml显著高于甲状腺结节患者(1.2±0.5)μIU/ml(t=12.750,P<0.01)。存在颈侧区淋巴结转移、高TNM分期、钙化组织、肿瘤直径≥1 cm患者TSH水平显著升高(t=12.676,4.940,11.149,6.803,P<0.01)。结论 TSH水平与甲状腺乳头状癌的发生和发展密切相关是预测淋巴结转移及分期的重要指标。
Objective To investigate the relationship between serum thyroid stimulating hormone level and lymph node metastasis in papillary thyroid carcinoma. Methods The clinical data of 127 patients with thyroid papillary carcinoma and 50 patients with benign thyroid nodules were retrospectively analyzed. We also analyzed the serum level of thyroid stimulating hormone and thyroid papillary carcinoma metastasized to cervical lymph nodes and other pathological data. SPSS 20. 0 software package was used for data analysis. The pathological data,TSH level and other measurement data of the patients were expressed as mean ± SD and examined by Student＇s t test. P〈0. 05 was statistically significant. Results The TSH level in thyroid cancer patients was（ 2.4 ± 0.7） μIU / m L and（ 1.2 ± 0.5） μIU /m L in patients with thyroid nodules. The TSH level of patients with thyroid carcinoma was significantly higher than that of patients with thyroid nodules（ t = 12. 750,P〈0. 01）.There was a significant increase in TSH levels in patients with metastasis to cervical lateral lymph nodes,TNM staging,calcification,and tumor diameter ≥ 1 cm（ t = 12. 676,4. 940,11. 149,6. 803,P〈0. 01）.Conclusion Serum thyroid stimulating hormone levels are closely related to the occurrence and development of papillary thyroid carcinoma,which is an important indicator for predicting lymph node metastasis and staging.
出处
《中华普外科手术学杂志（电子版）》
2015年第6期59-60,共2页
Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
关键词
甲状腺肿瘤
促甲状腺素
淋巴转移
Thyroid neoplasms
Thyrotropin
Lymphatic metastasis
