摘要
目的:探讨超声对女童性早熟的诊断价值及药物治疗后超声评估疗效的价值。方法:应用超声检测80例女童性早熟患儿子宫、卵巢大小及形态,对其中36例真性性早熟患儿进行促性腺激素释放激素类似物(GnRHa)治疗,并应用超声监测治疗前、治疗后8个月子宫、卵巢大小及形态变化,测定血清黄体生成素(LH)和卵泡刺激素(FSH),并与正常同龄女童进行对比。结果:观察组子宫、卵巢大小、卵泡直径、LH值、FSH值均较对照组大,差异均有统计学意义(t=7.13、10.16、6.93、11.35、9.64,P<0.05)。治疗8个月后子宫、卵巢容积、卵泡直径、LH值、FSH值基本恢复正常女童水平,差异均无统计学意义(t=1.94、1.08、2.98、0.96、1.36,P>0.05)。结论:超声检测对真性性早熟女童的检出率高,对其治疗后的疗效评估方面具有重要的临床价值。
Objective:To investigate the value of ultrasonography to the diagnosis of sexual precocity in girl and the value of the evaluation on effect after drug treatment in accordance with ultrasonography.Methods:To examine the volume and morphology of the uterus and ovary of girl patients with sexual precocity.Treat the 36 girl patients with true sexual precocity with GnRHa and monitor the changes in the volume and morphology of uterus and ovary through ultrasonography within the 8months before and after treatment,and determine LH and FSH and compare them with normal girls at the same age.Results:The volume of uterus and ovary were smaller.the diameter of follicle were longer and the value of LH and FSH were lager than that in control group,the differences were statistically significant(t=7.13,10.16,6.93,11.35,9.64,P<0.05),after 8months of treatment,The volume of uterus and ovary,the diameter of follicle,the value of LH and FSH all recovered and generally became as normal as that of the normal girls,the differences were not statistically significant(t=1.94,1.08,2.98,0.96,1.36,P>0.05).Conclusion:The relevance rate of true sexual precocity in girl was high if examining through ultrasonography and it is of great clinical value to the evaluation on curative effect after treatment.
出处
《数理医药学杂志》
2016年第1期18-19,共2页
Journal of Mathematical Medicine
关键词
超声
女童性早熟
子宫容积
卵巢容积
ultrasound
sexual precocity in girl
volume of uterus
volume of ovary