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前肾上腺髓质素在预测、评估脓毒症中的应用 被引量:1

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摘要 脓毒症是一种临床常见急症,伴随着人口老龄化和耐药菌株的不断出现,脓毒症的发病率正以1.5%--8.0%的速度逐年增长。脓毒症早期诊断以及干预不及时,可发展成严重脓毒症,甚至脓毒性休克,导致死亡[1]。其发展转归有众多复杂的机制参与,包括宿主对感染的反应以及氧的传输和利用障碍等。目前用于脓毒症诊断的实验室指标(白细胞计数、C反应蛋白)缺乏特异性,病原学检查虽具良好的特异性,但是常需4~7天才能获得结果,严重滞后于病情变化,不能满足早期诊断的目的,降钙素原及前心房尿钠肽对于脓毒症的早期诊断很有价值,但降钙素原对病毒及非典型致病菌导致的脓毒症,没有临床指导意义。
出处 《中国临床医生杂志》 2015年第12期19-20,共2页 Chinese Journal For Clinicians
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  • 1沈君,梁妤婷,左云龙,卢嘉铭,彭秋琰,熊雨美,洪燕.降钙素原与小儿脓毒血症相关性的研究[J].中国临床医生杂志,2013,41(2):52-54. 被引量:16
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