摘要
目的 观察口服达英35联合二甲双胍治疗肥胖型多囊卵巢综合症（PCOS）的疗效。方法 选取2010年6月~2014年6月我院收治的肥胖型PCOS患者80例,将其随机分为观察组和对照组,各40例。观察组采用达英35联合二甲双胍进行治疗,对照组单用达英35进行治疗,比较两组患者治疗前后体质量指数（BMI）、血清促黄体生成素（LH）、睾酮（T）、促卵泡素（FSH）、空腹血糖（FBG）、空腹胰岛素（FINS）、总胆固醇（TC）以及甘油三脂（TG）等指标变化。结果 治疗后,观察组总有效率明显高于对照组,差异有统计学意义（P〈0.05）;治疗后,观察组的BMI、LH、T、FSH、FBG、FINS、TC及TG较对照组显著降低,差异有统计学意义（P〈0.05）。结论 口服达英35联合二甲双胍治疗肥胖型PCOS,可有效降低患者性激素、血糖、胰岛素及血脂水平,提高疗效,值得临床推广与应用。
Objective To explore the effect of Dine-35 combined with metformin in treatment of obese polycystic ovary syndrome （PCOS）. Methods From June 2010 to June 2014, 80 cases of obese PCOS patients were randomly divided into observation group and control group, Observation group with Diane-35 combined with metformin treatment, control group with Diane-35 treatment, were compared between the two groups before and after treatment in patients with body mass index （BMI）, and serum levels of luteinizing generation prime （LH）, testosterone （T）, follicle stimulating hormone （FSH）, fasting blood glucose （FBG）, fasting insulin （fins）, total cholesterol （TC） and glycerin three fat （TG） and other indexes. Results After treatment, the total effective rate of observation group is higher than that of control group （P〈0.05） ; The BMI, LH, T, FSH, FBG, FINS, TC and TG of observation group significantly reduced than that of control group （P〈0.05）. Conclusion Dine-35 combined with metformin in treatment of obese PCOS can effectively lower the levels of hormone, blood glucose, asting insulin,and blood lipid, improve efficary, worthy of promotion and application.
出处
《实用妇科内分泌电子杂志》
2015年第9期183-184,共2页
Electronic Journal of Practical Gynecological Endocrinology
关键词
达英35
二甲双胍
多囊卵巢综合症
疗效
Dine-35
Metforrnin
Polycystic ovary syndrome
Curative effect
