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卵圆孔未闭与缺血性卒中的临床研究 被引量:5

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摘要 目的探讨缺血性卒中(包括脑梗死和短暂性脑缺血发作)患者卵圆孔未闭的发生率及其相关性。方法应用经颅多普勒超声(TCD)对100例缺血性卒中患者进行激活氯化钠试验检查,判断卵圆孔未闭情况。结果80例患者激活氯化钠试验未发现微泡栓子(卵圆孔未闭阴性组);20例患者激活氯化钠试验发现微泡栓子(卵圆孔未闭阳性组),发生率为20%(20/100),1~10微泡栓子15例,〉10微泡栓子4例,雨帘效应1例。两组性别构成、年龄、缺血性卒中构成、传统缺血性卒中危险因素(高血压、高血脂、冠心病、糖尿病、高同型半胱氨酸血症、吸烟、颈动脉斑块)发生率比较差异无统计学意义(P〉0.05);卵圆孔未闭阳性组颅内外血管病变发生率明显低于卵圆孔未闭阴性组[0比36.2%(29/80)],差异有统计学意义(P〈0.05)。而且卵圆孔未闭阳性组未发现明确的心源性栓子源、心房颤动、心肌梗死病史等。结论卵圆孔未闭可能是隐源性缺血性卒中的潜在原因。
出处 《中国医师进修杂志》 2015年第12期923-925,共3页 Chinese Journal of Postgraduates of Medicine
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