摘要
高氧暴露可引起新生儿慢性支气管肺疾病(BDP)及成人急性呼吸窘迫综合征(ARDS),这是一个复杂的病理生理过程.高氧所致的BDP可能与炎症因子等多种因素的相互作用有关,是婴幼儿时期的主要并发症和死亡原因。其发病机制一直是研究的热点,本文就高氧肺损伤中促炎因子及其他相关因素的相互作用及相关的治疗展望进行讨论。
High concentrations of inspired oxygen contribute to the pathogenesis of neonatal chronic bronchial pulmonary disease and adult acute respiratory distress syndrome,it＇s a very complicated pathophysiology progress. The BDP caused by high concentrations of inspired oxygenmight be related to the interaction of inflammatory factors and many other factors,also the main complications and death reason of infants and young children. Its pathogenesis has been a hot research. In this paper,the interaction of proinflammatory cytokines and other factors in the high oxygen lung injury and the prospect of the treatment are discussed.
出处
《齐齐哈尔医学院学报》
2015年第33期5082-5084,共3页
Journal of Qiqihar Medical University
基金
山东省医药卫生科技发展计划项目(编号2014WS0487)
关键词
高氧暴露
慢性支气管肺疾病
炎症因子
High oxygen exposure
Chronic bronchial pulmonary disease
Inflammatory factors
