摘要
目的:探讨去氧孕烯块雌醇片对治疗药物流产后阴道出血的临床效果。方法:将464名行药物流产孕囊完整排除的病例按照单双号顺序分为观察组(单数)和对照组(双数),两组各为232名。观察组在孕囊排出第3d常规给予去氧孕烯块雌醇片,每晚服用1片,连用21d;对照组暂不给予去氧孕烯块雌醇片。对两组孕囊排出后第10d仍有明显阴道出血的病例,均给予去氧孕烯块雌醇片每天早晚各1片(均于孕囊排除后21d停药)。结果:药物流产后观察组阴道出血量明显多于月经量的病例占20.3%,显著低于对照组(χ2=32.91,P<0.005);孕囊排出后10d内观察组止血的病例占92.2%,显著高于对照组(χ2=31.34,P<0.005);两组10d后仍有明显阴道出血的85名患者,给予去氧孕烯块雌醇片,每天早晚各1片处理,全部病例在(3.6±1.9)d止血;观察组药物流产后第一次月经量明显多于平素月经量的病例占24.1%,与未使用去氧孕烯块雌醇片的对照组无显著差异(χ2=2.47,P>0.05),但出血持续时间显著缩短(t=7.536,P<0.001)。结论:去氧孕烯块雌醇片能有效减少药物流产后阴道出血量和出血时间,降低了清宫率,避免了再次意外妊娠的发生,并缩短了下次月经持续时间。
Objectives： To investigate the clinical effect of marvelon on the treatment of vaginal bleeding after drug abortion. Methods： A total of 464 women with gestational sac completely discharged after drug abortion were randomly divided into observation group and control group according to the odd and even number sequence, the obser- vation group （odd number） and control group （even number）. In the observation group, marvelon was given 3 days after the gestation sac discharged for treatment, one tablet every night, for 21 days; the control group was not given marvelon. Women in two groups who still had significant vaginal bleeding on the tenth day after gestation sac dis- charged were treated with man, don two tablets every day （withdrawal 21 days after the gestation sac discharged）. Results： In the observation group, women whose vaginal bleeding after drug abortion was obviously higher than men- strual quantity accounted for 20. 3%, significantly lower than the control group （X2 =32.91 ,P 〈0. 005） ; Women in the observation group still bleeding 10 days after gestational sac discharged accounted for 92.2%, significantly higher than the control group （x2 =31.34, P 〈0. 005）. There were 85 patients in the two groups who still had vaginal bleed- ing 10 days after and were given marvelon twice everyday and all stopped bleeding （3.6± 1.9） d later. 24. 1% of women in the observation group had larger amount of menstruation than usual, without significant difference from that of the control group （X2 =2.47, P 〉 0. 05）, but the duration was shortened （t = 7. 536, P 〈 0. 001 ）. Conclusions： Marvelon can effectively reduce the amount and duration of vaginal bleeding after drug abortion, reduce the rate of curettage, avoid the occurrence of unexpected pregnancy again, and shorten the duration of next menstruation.
出处
《中国性科学》
2015年第12期76-79,共4页
Chinese Journal of Human Sexuality
