摘要
目的探讨我国T2DM患者中性粒细胞/淋巴细胞(NLR)与HbA_1c的关系。方法选取387例T2DM患者,根据HbA_1c水平分为HbA_1c≤6.0%组68例、6.0%<HbA_1c≤7.0%组165例和HbA1c>7.0%组154例,比较3组间HbA_1c与NLR的差异及二者的相关性。结果 T2DM患者NLR随HbA_1c水平升高而增高[(2.09±0.57)vs(2.17±0.51)vs(2.68±0.48),P<0.01]。NLR与HbA_1c水平呈正相关(r=0.509,P<0.01)。Logistic多元回归分析结果显示,影响HbA_1c水平的危险因素为NLR及FPG。结论 NLR、FPG与T2DM患者HbA_1c水平呈正相关。
Objective To investigate the relationship between neutrophil-lymphocyte ratio（NLR）and HbA_1 c in patients with T2DM in China. Methods A total of 387 patients with T2DM were enrolled in this study.All the subjects were divided into three groups according to their HbA_1c levels.HbA_1c≤6.0% group（n=68）,6.0%〈HbA_1c≤7.0% group（n=165）and HbA_1c〉7.0% group（n=154）.The correlation and differences between HbA_1c and NLR were calculated among the three groups. Results NLR values were significantly increased together with increase of HbA_1c levels in T2DM patients[（2.09±0.57）vs（2.17±0.51）vs（2.68±0.48）,P〈0.01）].NLR was positively correlated with HbA_1c in T2DM patients（r=0.509,P〈0.01）.Logistic regression analysis showed that NLR and FPG were risk factors for HbA_1c. Conclusion NLR and FPG were positively correlated with HbA_1 c in T2DM patients.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2015年第12期1077-1080,共4页
Chinese Journal of Diabetes
基金
南方医科大学青年科技人员培育项目(PY2013NO51)
