摘要
目的探讨胺碘酮用于冠心病慢性心力衰竭合并室性心律失常的治疗效果。方法以我院收治的108例冠心病慢性心理衰竭合并室性心律失常患者为研究对象,随机分成两组,对照组(54例)采取常规治疗,观察组(54例)常规治疗基础上加用胺碘酮治疗,比较两组的治疗效果,记录治疗期间不良反应。结果观察组心率、左室射血分数、室性早搏总数和QT离散度改善效果明显好于对照组;观察组心功能改善有效率83.33%,心律控制有效率88.89%,对照组心功能改善有效率59.26%,心律控制有效率64.81%,组间疗效比较差异显著;两组治疗期间未见死亡病例,对照组治疗期间不良反应发生率9.26%,观察组不良反应发生率22.22%,组间比较无显著差异。结论胺碘酮提高冠心病慢性心衰合并室性心律失常的治疗效果,可进一步推广应用。
Objective To investigate the effect of amiodarone for chronic heart failure of coronary heart disease with ventricular arrhythmia. Methods 108 cases patients with chronic heart failure of coronary heart disease with ventricular arrhythmia in our hospital were regarded as the research object.They were randomly divided into 2 groups. Control group（54 cases） was treated by conventional treatment. Observation group（54 cases） was treated by amiodarone on the basis of conventional treatment.The therapeutic effect was compared,and adverse reaction was recorded during treatment. Results Heart rate,left ventricular ejection fraction,ventricular total and QT dispersion improvement of the observation group were significantly better than the control group.Heart function improvement rate of the observation group was 83.33%,and rhythm control rate was 88.89%.Heart function improvement rate of the control group was 59.26%,and rhythm control rate was 64.81%.The effect between groups had significantly difference.There was no death in the 2 groups during the treatment.Adverse reaction incidence of the control group was 9.26% during treatment.The adverse reaction incidence of the observation group was 22.22%.There was no significant difference between groups. Conclusion Amiodarone increased treatment effect of chronic heart failure of coronary heart disease with ventricular arrhythmia,which is worthy of application.
出处
《中国医药科学》
2015年第20期28-30,36,共4页
China Medicine And Pharmacy
关键词
胺碘酮
冠心病慢性心力衰竭
室性心律失常
治疗效果
Amiodarone
Coronary heart disease and chronic heart failure
Ventricular arrhythmia
Therapeutic effect
