摘要
目的:观察二陈汤加味治疗小儿非感染性腹泻的临床疗效和安全性,为中药治疗此病提供治疗思路。方法:选取本院门诊或病房收治的80例非感染性腹泻患儿,按照随机平均的方法分为观察组和对照组,两组患儿均给予补液及饮食等基础治疗,观察组除采取基础治疗外还予二陈汤加味方口服,对照组则予蒙脱石散口服。观察两组患儿治疗前、后的临床症状、生命体征及各项实验室指标的变化。结果:两组患儿的痊愈、显效率比较,观察组患儿明显优于对照组,具有显著性差异(P<0.05),但两组患儿总有效率相比,则无显著性差异(P>0.05)。两组患儿大便次数的缓解时间经统计分析,观察组患儿明显优于对照组,具有显著性差异(P<0.05)。两组患儿治疗后的临床症状评分相比,在饮食、呕吐、腹胀、口渴、精神及面色各项的评分具有显著性差异(P<0.05),但在粪便性状及大便次数这两项的评分则不具有显著性差异(P>0.05)。其中观察组患儿在治疗前、后的各项症状的评分相比,在粪便性状、大便次数、饮食、呕吐、腹胀、口渴、精神及面色各项的评分经统计分析,均具有显著性差异(P<0.05)。从不良反应来看,对照组有3例婴儿在服药期间出现了呛咳和呕奶的现象,2例患儿服药后出现了便秘的副反应,而观察组则无明显的不良反应。结论:使用二陈汤加味治疗小儿非感染性腹泻的临床疗效显著,可提高患儿机体的调节能力,改善其整体状况,无明显的毒副反应及不良反应,安全性高。
Objective： To explore the clinical effects and safety of Erchen Decoction to treat the young children with non- infectious diarrhea so as to seek the more effective method and a new way of Chinese medicine to treat a young children with infectious diarrhea. Methods： 80 young children with non- infectious diarrhea from June 2013 to August 2014 in the hospital were chosen as the research objects,and analyzed the clinical information of the patients,they were divided into two groups,named the experimental group and the control ledgroup,40 cases in each group. Both of the two groups were given the foundational therapy including food control and fluid infusion. At the same time their acid- base equilibrium were corrected. The experimental group were given Jiawei Erchen Decoction,and the controlled group were given the Smectite Powder. Then the anteroposterior symptom,physical sign,the clinical symptom integral and the laboratory index were observed. Results： Compared the curative effects of the two group,the experimental group was superior than the controlled group（ P 〈0. 05）,and there was a significant difference between the two groups,while there was no significant difference between the two groups on the total effectiveness（ P 〉0. 05）.There was a significant difference on the time that bowel movement times alleviates（ P 〈0. 05）. Comparing the score after treatment： there was a significant difference on the vomit,diet,thirsty,distension of the abdomen,facial color,spiritual,（ P 〈0. 05）,but in bowel movement times and excrement character（ P 〉0. 05）. Comparing the score that before and after treatment in Jiawei Erchen Decoction group,there was a significant difference on bowel movement times,excrement character,vomit,diet,thirsty,distension of the abdomen,facial color,spiritual all（ P 〈0. 05）. The medicine untoward effects,there were 3cases appeared chokes and vomits milk and 2cases had the constipation in the controlled group while in there was no obviously untoward in the experimental group. Comparing the bowel p H before and after treatment in two groups,there was a significant difference（ P 〈0. 05）. Conclusion： Jiawei Erchen Decoction has a good clinical effect on non- infectious diarrhea which is better than the Smectite and can improve the modulation ability of young children and improve their health,enhance the curative effect. Patients in the experimental group have no obvious side effect so it is safe and feasible in the clinical application. It is also helpful to fit for the bowel p H.
出处
《四川中医》
2015年第12期140-143,共4页
Journal of Sichuan of Traditional Chinese Medicine
关键词
非感染性腹泻
小儿
加味二陈汤
临床疗效
安全性
Non-infectious Diarrhea
Young Children
Jiawei Erchen Decoction
Clinical effects
Safety
