摘要
黄酮木脂素类化合物作为一类特殊类型的天然黄酮类化合物,由于其显著的保肝和抗癌作用,备受人们关注。然而由于其结构的复杂性和相似性,给分离工作和绝对构型的确定带来很大困难。本文综述了近30年来圆二色(CD)谱法在黄酮木脂素类化合物绝对构型测定中的一些规律及应用,以期为该类化合物绝对构型测定提供有益的参考。
Flavonolignans,as a special class of flavonoid,have attracted people＇s attention for their remarkable hepatoprotection and anti-cancer activity. However,separation of flavonolignans and identification of their absolute configuration have met with great challenges due to the complexity and similarity of structures. The circular dichroism（CD） rules and their application in analyzing the absolute configuration of flavonolignans are summarized in the review and hopefully it may be helpful for the structure elucidation of flavonolignans.
出处
《国际药学研究杂志》
CAS
CSCD
北大核心
2015年第6期794-801,共8页
Journal of International Pharmaceutical Research
基金
国家自然科学基金资助项目(81172958)
关键词
圆二色谱法
黄酮木脂素
绝对构型
circular dichroism（CD）
flavonolignan
absolute configuration
