摘要
目的探讨颅骨缺损修补术对患者短期脑灌注及神经功能的影响。方法 2013年8月～2014年12月收治颅骨缺损患者20例（GCS评分为8～12分,颅骨缺损时间为3～4个月）,均行数字化钛网颅骨缺损修补术,术前、术后2周进行320-CT脑灌注检查,同时在上述时点采用日常生活能力量表（ADL）评估神经功能。结果颅骨成形术后2周,颅骨缺损局部及缺损边缘2 cm范围内的脑血流量、脑血容量、平均通过时间、达峰时间与术前比较明显改善（P〈0.05）;术后2周患者ADL评分[（67.41±19.73）分]较术前[（42.43±20.36）分]显著改善（P〈0.01）。结论颅骨修补术能够使缺损局部及周围脑组织脑灌注增加、神经功能改善。
Objective To explore the effects of cranioplasty on the cerebral peffusion and neurological function in the patients with skull defects. Method The cranioplasty was performed 3 months after the decompressive craniectomy from January, 2013 to August, 2014 in 20 patients in whom GCS ranged from 8 to 12 points and the cerebral peffusion and neurological function were assessed respectively by a 320-detector row whole-brain computed tomography （CT） scan and activity of daily living scale （ADL） before the cranioplasty and 2 weeks after the surgery. Results The peffusion parameters including the cerebral blood flow, cerebral blood volume, mean transit time, time to peak were significantly improved in the regions of the skull defect and defect edge within 2 cm 2 weeks after the cranioplasty compared with the preoperative those （P〈0.05）. ADL [（67.41± 19.73） points] was significantly higher 2 weeks after the cranioplasty than that [（42.43 ± 20.36） points] before the cranioplasty （P〈0.01）. Conclusions The cranioplasty surgery may not only improve aesthetic appearance and protect the brain tissues, but also significantly improve the cerebra] per[usion and neurological function in the patients with skull defects, in whom the cranioplasty should be performed as early as possible.
出处
《中国临床神经外科杂志》
2015年第12期736-738,共3页
Chinese Journal of Clinical Neurosurgery
关键词
颅骨缺损
颅骨修补术
脑灌注
神经功能
Skull defects
Cranioplasty
Cerebral Perfusion
Neurological function
