摘要
目的探讨骨创治疗仪对于原发Ⅱ型骨质疏松症患者肋骨骨折的临床疗效。方法参照临床流行病学(DME)原则,纳入符合标准的原发Ⅱ型骨质疏松症合并肋骨骨折受试者43例,随机分为观察组(21例,其中男8例,女13例,平均年龄65.7岁,平均体重67.3kg)、对照组(22例,其中男7例,女15例,平均年龄66.2岁,平均体重68.1kg),两组均给予基础药物治疗:钙尔奇D片、骨化三醇胶丸,分别给予肋骨带制动或肋骨带制动联合骨创治疗仪治疗,在治疗前、后检测患者肋骨正斜位DR、右髋骨密度、血清骨碱性磷酸酶,由2名专业医师对患者的疼痛程度评分进行评定。结果基线比较,组间比较均无差异(P>0.05)。疗效结果统计显示:观察组患者干预后疼痛评分较干预前明显降低(P<0.01),较对照组亦明显降低(P<0.01),观察组右髋BMD干预后较干预前有升高趋势(P>0.05),BALP组内比较观察组干预前后显著提高,对照组干预前后无统计学差异(P>0.05);观察组CTX干预后较干预前明显降低(P<0.01),与对照组干预后比较观察组CTX亦明显降低,提示干预后观察组骨形成增加,骨吸收减少。观察组干预后GH、VT、SF、MH明显提高,与对照组干预后比较,观察组VT、MH提高具有统计学差异(P<0.05),提示干预后精力及精神健康状况明显好转。结论骨创治疗仪能够降低骨转换,但短期内对患者骨密度未见明显影响,对老年性肋骨骨折具有良好的止痛作用,有利于提高患者精力、社会功能、精神健康状态以及生活自理能力。
Objective To exploretheefficacy of bonetherapeutic apparatus on thetreatment of rib fractures in patients with primary typeII osteoporosis. Methods According to theprincipleof clinical epidemiology（ DME）,43 cases with rib fractures who met thestandard of primary osteoporosis typeII wereincluded. They wererandomly divided into observation group（ 21 cases,8 males and 13 females,with an averageageof 65. 7 years and an averageweight of 67. 3 kg） and thecontrol group（ 22 cases,7males and 15 females,with an averageageof 66. 2 years and an averageweight of 68. 1 kg）. Patients in thetwo groups received basic therapy： including CaltrateD and Calcitriol. They weretreated with rib with brakeor rib with brakecombined with bonetherapeutic apparatus,respectively. Beforeand after thetreatment,obliquerib X-ray,bonemineral density of theright hip,and serum bonealkalinephosphataseweredetected. Thescoreof thepain degreeof thepatients was assessed by 2 professional doctors.Results At baseline,therewas no differencebetween the2 groups（ P〉0. 05）. Theresults showed that thepain scorein theobservation group was significantly lower than that in thecontrol group（ P〈0. 01）. BMD of theright hip in theobservation group showed increased trend after thetreatment compared to that beforetheintervention（ P〉0. 05）. BALP increased in theobservation group after theintervention but it did not changein thecontrol group（ P〉0. 05）. CTX decreased significantly in theobservation group and it was lower than that in thecontrol group（ P〈0. 01）,indicating that boneformation increased and boneresorption decreased in theobservation group. GH,SF,VT,and MH significantly improved in theobservation group,and theincreasewerestatistically different compared to thecontrol group（ P〈0. 05）,indicating that themental health status in theintervention group was significantly improved. Conclusion Boneinvasivetherapy can reduceboneturnover,but it has no significant effect on bonemineral density in theshort term. It has a good analgesic effect on senilerib fractures,which is beneficial to improvethepatient＇s energy,social function,mental health status,and self-living ability.
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2015年第12期1491-1494,共4页
Chinese Journal of Osteoporosis
关键词
肋骨
骨折
骨创治疗仪
原发Ⅱ型骨质疏松症
Ribs
Fracture
Bone invasive therapeutic apparatus
Primary type II osteoporosis
