摘要
胰腺癌是恶性程度最高的消化系统恶性肿瘤之一，其手术切除率低、早期即可转移，且胰腺癌对放化疗均不敏感，目前治疗效果不满意。寻找有效的治疗方式是目前胰腺癌治疗亟待解决的问题。近10余年来胰腺癌基础研究促进了免疫治疗在胰腺癌中的应用，同时胰腺癌免疫治疗的一些前期临床实验也取得了一些鼓舞人心的结果。本文将就胰腺癌免疫治疗在近年来所取得的一些成果及应用现状、前景作一综述。
Pancreatic adenocarcinoma is one of the most highly malignant digestive system cancers, and current therapeutic strategies are often unsatisfactory. It is associated with a high mortality rate because of low resection rate, early metastasis, and poor ehemoradiotherapy response. Identification and development of more efficacious therapies is urgently needed. The basic research promoted the development of immunotherapy for pancreatic cancer, and immunotherapy offered encouraging results in some preclinical trials during the last decade. The aim of this review is to summarize the recent advances in immunotherapy and to evaluate the future perspectives of immunotherapy in the treatment of pancreatic adenocarcinoma.
出处
《中国医师杂志》
CAS
2015年第12期1790-1793,共4页
Journal of Chinese Physician
