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BCLC B期肝癌术后行索拉非尼治疗的疗效分析 被引量:2

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摘要 目的:探讨手术切除后服用索拉非尼治疗巴塞罗那临床肝癌分期系统(BCLC)B期肝细胞肝癌(以下简称肝癌)的临床疗效。方法:回顾性收集2011年1月至2013年12月因BCLC B期肝癌在四川大学华西医院肝脏外科接受手术切除并于术后服用索拉非尼的患者资料,以及同期仅行手术切除的患者资料,1:2配对,做病例对照研究,比较2组患者的生存时间及肿瘤复发时间。共纳入63例病例,观察组21例,对照组42例。结果:2组中位生存时间分别为25.0个月和17.7个月,差异有统计学意义(P=0.025);肿瘤复发时间分别为9.6个月和5.7个月,差异无统计学意义(P=0.574)。结论:手术切除联合索拉非尼治疗BCLC B期肝癌是安全的,并且可以延长患者的中位生存时间,是一种值得考虑的治疗方案。
出处 《温州医科大学学报》 CAS 2015年第12期929-931,共3页 Journal of Wenzhou Medical University
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