摘要
目的探讨超敏C-反应蛋白（hs-CRP）检测在新生儿急性泪囊炎治疗过程中的临床意义。方法以本院收治的64例新生儿急性泪囊炎患儿作为研究对象,采用控制感染并及时行泪道冲洗和泪道探通法进行治疗,治疗过程中采用免疫比浊法检测患儿血清hs-CRP水平,并结合临床症状进行综合分析。结果64例患儿全部治愈。入院时患儿血清hs-CRP平均水平为（21.25±9.78）mg/L,显著高于正常参考范围的（0-8）mg/L;治疗3 d后血清hs-CRP平均水平为（13.46±4.55）mg/L,与入院时比较差异具有统计学意义（t=24.1,P〈0.01）;治愈后患儿血清hs-CRP平均水平为（2.60±1.88）mg/L,与治疗3 d后水平比较,差异具有统计学意义（t=19.2,P〈0.01）。结论正规治疗急性泪囊炎新生患儿的同时检测其血清hs-CRP水平的变化对临床观察以及预后判断具有重要的临床意义。
Objective To investigate the clical significance of changes of serum hypersensitive C-reactive protein（hs-CRP） in patients with neonatal acute dacryocystitis（NAD）.Methods The levels of serum hs-CRP（with immuno-turbidity） were detected in 64 patinets with NAD before treatment and treatments for 3 days and after cure.All clinical features were comprehensively analyzed.Results Total of64 children were all cured.The mean level of serum hs-CRP was（21.25 ± 9.78） mg/L on admission.It was significantly higher than the normal reference range（0-8 mg/L）.After 3 days of treatment,the mean level of serum hs-CRP dropped down to（13.46 ± 4.55） mg/L,with significant difference compared with that of 3 days after treatment（t = 24.1,P 〈0.01）.After cure,the mean level of serum hs-CRP was（2.60± 1.88） mg/L,there were the significant difference compared with the previous level（t = 19.2,P 〈0.01）.Conclusions Measurement of the changes of serum hs-CRP levels in therapeutic process might be important for the outcome prediction in NAD.
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2015年第6期91-93,共3页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
关键词
新生儿
急性泪囊炎
超敏C-反应蛋白
Newborn
Acute dacryocystitis
Hypersensitive C-reactive protein
