摘要
日本胃癌治疗指南建议根据分期的不同来选择早期胃癌的治疗策略。早期胃癌的治疗与淋巴结转移状态密切相关,对淋巴结转移状态的精确评估关系到治疗方案的选择及患者的预后。目前评估淋巴结转移状态的方法主要有:根据临床病理学因素评估、根据影像学和分子标志物评估以及前哨淋巴结示踪活组织检查技术。对于适合内镜下黏膜下层切除术(EMR)或内镜下黏膜下层剥离术(ESD)治疗的早期胃癌建议使用二步法来管理;对于EMR或ESD适应证之外的早期胃癌可结合使用影像学和分子标志物及前哨淋巴结示踪活组织检查技术来判断淋巴结转移状态。
Japanese gastric cancer treatment guidelines list options for treatment of each stage of early gastric cancer (EGC). The treatment of EGC is closely related to the lymph node metastasis, and the accurate prediction of lymph node metastasis is related to the choice of the treatment options and the prognosis of the patients. The lymph node metastasis of EGC is evaluated according to the clinicopathological factors, imaging, molecular markers and sentinel lymph node (SLN) tracer biopsy. A two-step method for the management of EGC treated with endoscopic mucosal resection/endoscopic submueosal dissection (EMR/ESD) is recommended. While for those EGC patients not suitable to receive EMR/ESD, imaging or molecular marker and SLN tracer biopsy technology are applied to determine lymph node status.
出处
《中华消化外科杂志》
CAS
CSCD
北大核心
2016年第1期93-96,共4页
Chinese Journal of Digestive Surgery
关键词
胃肿瘤
早期
淋巴结转移
临床病理因素
分子标志物
前哨淋巴结
Gastric neoplasms, early
Lymph nodemetastasis
Clinicopathological factors
Molecular marker
Sentinel lymph node