摘要
目的探讨影响结直肠癌术后复发转移的临床病理因素，以期提高结直肠癌的疗效。方法回顾性分析2009年1月至2013年12月在该院行结直肠癌手术治疗的212例Ⅰ～Ⅲ期结直肠癌患者的临床病理资料及随访资料，选择对结直肠癌术后复发转移可能产生影响的临床病理因素进行单因素及多因素Logistic回归分析。结果单因素分析显示，T分期、大体类型、合并梗阻或穿孔、术后淋巴血管侵犯与术后局部复发有关（P〈0．05）；年龄、肿瘤大小、淋巴结转移、T分期、分化程度、合并梗阻或穿孔、术后淋巴血管侵犯与术后远处转移有关（P〈0.05）。多因素Logistic回归分析显示，年龄、肿瘤太小、分化程度是影响结直肠癌术后转移的独立危险因素（P〈0．05）；复发的多因素Logistic回归分析结果差异无统计学意义（P〉0.05）。结论年龄、肿瘤大小、分化程度是影响结直肠癌术后转移的独立危险因素。
Objective To investigate the clinical pathological factors related to recurrence and metastasis of colorectal cancer patients treated with resection,expect to improve the treatment effects. Methods The elinicopathologic and follow-up data of 212 patients with stage I -- 111 colorectal cancer patients treated with resection from January 2009 to December 2013 were retrospectively analyzed by univariate and multivariate Logistic regression methods. Results Univariate analysis showed that T staging systems,gross type,intestinal obstruction or perforation,lymphatic and vascular invasion were correlated to recurrence of coloreetal cancer after operation（P〈0.05） ; age, tumor size. lymph node involvement, T staging systems, histological differentiation, intestinal obstruction or perforation,lymphatic and vascular invasion were correlated to metastasis of colorectal cancer after operation（P〈 0.05）. Multivariate Logistic regression analysis showed that age, tumor size and histological differentiation were independent factors for metastasis rate of colorectal cancer after operation（P〈0.05）. There were no significant differences in Logistic regression analysis for recurrence（P〈0.05）. Conclusion Age, tumor size and histological differentiation are independent factors for metastasis rate of colorectal cancer after operation.
出处
《重庆医学》
CAS
北大核心
2016年第2期205-208,共4页
Chongqing medicine
关键词
结直肠肿瘤
手术后期间
肿瘤复发
肿瘤转移
危险因素
因素分析
统计学
colorectal neoplasms
postoperative period
neoplasm recurrence
neoplasm metastasis
risk factors
faetor analysis, statistical
