摘要
本研究报道了一种新颖的、模拟口腔环境的仿生修复牙齿的方法。利用具有良好生物相容性的多巴胺在牛牙牙本质表面自聚合形成聚多巴胺层(PDA)使牙本质表面功能化,进而诱导羟基磷灰石从模拟唾液中向牙本质表面沉积。XPS、XRD、SEM和EDS表征分析表明:聚多巴胺层的涂覆有利于牙本质表面羟基磷灰石晶体的结晶生长,可提高羟基磷灰石再矿化层与牙本质表面的结合力;多巴胺溶液浓度为2 mg/m L时,牙本质表面聚多巴胺层的沉积效果最佳。
A novel and biomimetic restoration method for teeth by soaking in a simulated oral environment was reported. A biocompatible polydopamine （PDA） layer was deposited on the surface of dentin via dopamine polymerization to function- alize the surface to induce deposition of hydroxyapatite crystals. The samples were characterized by means of XPS, XRD, SEM and EDS. Results show that the coating ofpolydopamine layer induces the growth of hydroxyl apatite crystal on dentin surface, and improve the binding force between the hydroxyl apatite layer and the dentin surface. The optimized concentra- tion of dopamine solution is 2 mg/mL for the uniform deposition of PDA layer on the dentin surface.
出处
《无机材料学报》
SCIE
EI
CAS
CSCD
北大核心
2016年第1期95-99,共5页
Journal of Inorganic Materials
基金
国家杰出青年科学基金(51325203)~~
关键词
仿生材料
多巴胺自聚合
牙齿再矿化
结晶生长
biomimetic materials
polymerization of dopamine, mineralization of teeth
crystal growth
