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宫颈癌治疗中子宫动脉介入化疗栓塞术的应用观察 被引量:2

Uterine arterial interventional chemoembolization in treatment of cervical cancer
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摘要 目的 探讨子宫动脉介入化疗栓塞术对宫颈癌患者临床治疗效果.方法 收集我院2012年1至7月收治的宫颈癌患者80例,并行前瞻性研究且随机分为两组,每组40例,实验组患者给予子宫动脉介入化疗栓塞术治疗,对照组患者则给予全身静脉化疗,比较两组患者近期治疗效果、第7天阴道流血缓解情况、相关临床指标与远期生存率.结果 两组患者近期治疗效果差异不具有统计学意义(P>0.05);实验组患者治疗后第7天阴道流血缓解情况显著优于对照组,差异具有统计学意义(P<0.01);实验组患者手术间隔时间为(18.51±2.65)d、术中出血量为(341.78±50.81) ml,显著低于对照组[(23.89±3.24)d,(539.16±61.78) ml],差异具有统计学意义(P<0.01);两组患者手术时间差异不具有统计学意义(P>0.05);两组患者3年内存活率与死亡率差异不具有统计学意义(P>0.05).结论 子宫动脉介入化疗栓塞术对宫颈癌患者临床治疗效果显著,具有借鉴性. Objective To investigate the clinical curative effect of uterine arterial interventional chemoembolization in the treantment cervical cancer patients.Methods 80 cervical cancer patients admitted into our hospital from January to July, 2012 were collected for prospective study and were randomly divided into an experimental group and a control group, 40 cases for each group.The experimental group was treated with uterine arterial interventional chemoembolization and the control group with systemic vein chemotherapy.The short-term curative effect, the remission of colporrhagia on the seventh day, and the relevant clinical indicators and long-term survival rate of these two groups were compared.Results There was no statistical difference in short-term curative effect between these two groups (P〉0.05).The remission of colporrhagia on the seventh day was significantly better, the operational interval [(18.5 1±2.65) d vs.(23.89±3.24) d] was significantly shorter, and the intraoperative bleeding volume [(341.78±50.8 1)ml vs.(539.16±61.78)ml] was significantly lower in the experimental group than in the control group, with statistical differences (P〈0.01).There was no statistical differences in operation time and the survival rate and mortality rate within three years between these two groups (P〉0.05).Conclusions Uterine arterial interventional chemoembolization for cervical cancer is effective and is of reference in clinical practice.
作者 赵延吉
出处 《国际医药卫生导报》 2016年第2期168-170,共3页 International Medicine and Health Guidance News
关键词 宫颈癌 子宫动脉介入化疗栓塞术 治疗效果 阴道流血 生存期 Cervical cancer Uterine arterial interventional chemoembolization Curative effect Colporrhagia Survival time
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