摘要
目的对比分析老年患者甲状腺结节切除术和超声引导下微波消融(MWA)的临床效果和安全性。方法回顾分析2008年2月—2014年7月收治的甲状腺结节老年患者122例,其中50例施行甲状腺切除手术,72例患者选择超声引导下MWA治疗。观察两组的手术时间、出血量、住院时间、手术后并发症、术后甲状腺相关激素变化情况。结果开放手术组患者对比于MWA组手术时间长,术中出血多,术后局部不适发生率高,总的并发症多且住院时间长,差异均有统计学意义。开放手术患者术后血清TT4、血清FT3、血清FT4较术前降低而血清TSH明显升高。术前术后血清激素比较差异有统计学意义。而MWA组血清激素水平手术前后比较,差异无统计学意义。结论老年患者甲状腺疾病选择MWA治疗,安全可行而且效果明显,有可能成为老年患者治疗的首选。
Objective To evaluate the clinical efficacy and safety of surgical resection and ultrasound-guided microwave ablation in treating thyroid nodules in aged patients, and to compare the therapeutic results between the two methods. Methods The clinical data of 122 aged patients with thyroid nodules, who were admitted to authors＇ hospital during the period from February 2008 to July 2014, were retrospective analyzed. Of the 122 patients, 50 received surgical resection （surgery group） and 72 underwent ultrasound-guided microwave ablation （MWA group）. The operation time, amount of blood loss, hospitalization days, postoperative complications and postoperative changes of thyroid-related hormone levels were recorded. Results The operation time was longer and the amount of blood loss was larger in the surgery group than those in the MWA group; also in the surgery group the incidence of local discomfort and the occurrence of complications were higher, and the hospitalization time was longer than those in the MWA group. The differences between the two groups were statistically significant. After the treatment, in the surgery group the postoperative serum TT4, serum FT3 and serum FT4 levels were decreased, while the postoperative serum TSH was obviously increased, these changes were statistically significant when compared with the preoperative levels. In MWA group, the postoperative changes in serum thyroid-related hormone levels were not statistically significant when compared with the preoperative ones. Conclusion For the treatment of thyroid nodules in aged patients, ultrasound-guided microwave ablation is safe, feasible and effective. This technique may become the first choice of treatment for thyroid nodules in aged patients.
出处
《介入放射学杂志》
CSCD
北大核心
2016年第1期44-47,共4页
Journal of Interventional Radiology
关键词
老年人
甲状腺结节
切除手术
微波消融
超声引导
the aged
thyroid nodule
resection
microwave ablation
ultrasound guidance
