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老年心脏瓣膜病合并肺动脉高压患者行瓣膜手术疗效的影响因素 被引量:6

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摘要 目的探讨老年心脏瓣膜病合并肺动脉高压(PH)患者行瓣膜手术疗效的影响因素。方法选取280例老年心脏瓣膜病合并PH行瓣膜手术患者,行手术前后左心室射血分数(LVEF)、肺动脉收缩(PASP)及术后相关并发症、死亡率对比,探讨性别、年龄、心功能分级、术前PASP分级对手术疗效的影响。结果经瓣膜手术后,患者PASP与LVEF水平较术前明显好转(P<0.05);年龄≥70岁组患者手术前后PASP变化值及LVEF变化值均小于<70岁组,而并发症发生率及死亡率均显著高于<70岁组(P<0.05)。性别在所有患者统计指标中差异均无统计学意义(P>0.05);术后PASP值与心功能等级呈正比,手术前后PASP差值越小,LVEF值越低,手术前后LVEF差值越大,并发症及死亡率也越大(P<0.05)。术前术后PASP值变化越大,术后并发症及死亡率显著增加(P<0.05)。结论老年心脏瓣膜病合并PH患者行瓣膜手术的治疗疗效与年龄有关,与性别无关;术前心功能越差,手术疗效越差;术前PASP值越高,手术疗效亦越差,因此,术前因注意和控制高危因素。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第3期670-672,共3页 Chinese Journal of Gerontology
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参考文献13

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