摘要
急性肝损伤涉及短期内突发的肝细胞损害,其病因较多,机理复杂。现代医学认为急性肝损伤的发生与中毒、病毒性肝炎、免疫、血管障碍等相关。本文基于急性肝损伤发病原因类型,对急性肝损伤中药治疗的研究进展进行综述,为急性肝损伤有针对性的预防、治疗的新药研发提供理论依据。中药在急性肝损伤治疗方面有很大前景,表现出其特殊的优势,包括其单方、复方及提取物似乎对急性肝损伤的保护作用更为广泛。根据急性肝损伤的发病机理,并结合现代医学急性肝损伤药物治疗的分析,选用合适的药物对于药物评价、机制研究、临床防治救治急性肝损伤具有十分重要的意义。
Acute hepatic injury involves the emergent hepatocellular damage,the cause of which are many and the pathogenesis is complex. Modern medicine believes that the occurrence of acute hepatic injury may be associated with chemical damage,viral hepatitis,immunological etiologies,vascular disorders,etc. Based on the types of acute hepatic injury,investigating and summarizing Chinese medicine for acute hepatic injury thoroughly may provide a reference for specific prevention and treatment. Chinese medicine has wide prospects on the treatment of acute liver injury and presents its own advantages,in addition,it seems that the protection of Chinese medicine including herbs,compound and extracts is more widely applied to acute hepatic injury. According to the pathogenesis of acute hepatic injury,combined with analysis of drug treatment for acute hepatic damage from the perspective of modern medicine,it has important significance to select appropriate drugs for drug evaluation,mechanism research,clinical prevention and treatment of acute hepatic injury.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2016年第2期170-174,共5页
Chinese Journal of New Drugs
基金
国家自然科学基金(81360676)
关键词
急性
肝损伤
中药治疗
acute
hepatic injury
Chinese medicine treatment
