摘要
目的评价雷公藤多苷联合米诺环素治疗红斑、丘疹脓疱期玫瑰痤疮的临床疗效和安全性。方法入选的45例玫瑰痤疮患者通过随机数字表法随机分为两组,治疗组(23例)予口服雷公藤多苷及米诺环素,对照组(22例)仅予口服米诺环素,疗程均为6周。结果治疗结束时,治疗组有效率82.61%,对照组有效率50.00%,差异有统计学意义(P<0.05)。治疗过程中均未出现严重不良反应。结论雷公藤多苷联合米诺环素治疗玫瑰痤疮安全而有效。
Objective To evaluate the efficacy and safety of tripterygium wilfordii polyglycoside combined with minocycline in the patients with erythema and papulopustular ache rosacea. Methods Forty-five cases of patients with ache rosacea in accordance ruth the random number table were divided into two groups. Twenty-three cases of treatment group were treated with tripterygium wilfordii polyglycoside combined with minocycline,while 22 cases of control group were treated with minocycline. The effects were observated for 6 weeks. Results The response rates were 82. 61% and 50. 00% respectively. There was significant difference between the treatment group and the control group （ P 〈0. 05 ）. Conclusion Tripterygium wilfordii polyglycoside combined with minocycline for acne rosaeea is safe and effective.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2016年第2期214-215,218,共3页
The Chinese Journal of Dermatovenereology
关键词
雷公藤多苷
米诺环素
玫瑰痤疮
Tripterygium wilfordii pelyglycoside
Minocycline
Acne rosaeea
