摘要
目的:探讨常规体外受精(IVF)正常形态精子百分率是否会影响获单卵患者的临床结局。方法:选择2013年1月至2015年1月在本院生殖中心接受常规IVF治疗且获卵数为1的256对夫妇,根据正常形态精子百分率的不同分为两组,其中正常形态精子百分率<4%组134例,正常形态精子百分率≥4%组122例,比较两组间的无可移植胚胎周期发生率、受精率、卵裂率、正常受精率、异常受精率、优胚率及可用胚胎率。其中新鲜移植周期共75例,正常形态精子百分率<4%组43例,正常形态精子百分率≥4%组32例,比较两组间的种植率、临床妊娠率及流产率。结果:正常形态精子百分率<4%组和正常形态精子百分率≥4%组的无可移植胚胎周期发生率、受精率、卵裂率、正常受精率、异常受精率、优胚率及可用胚胎率差异无统计学意义(P>0.05)。新鲜移植周期中,正常形态精子百分率<4%组和正常形态精子百分率≥4%组的种植率、临床妊娠率及流产率差异也无统计学意义(P>0.05)。结论:正常形态精子百分率不影响单卵患者常规体外受精的临床结局。
Objective： To investigate the influence of the rate of morphologically normal sperm （MNS） on the clinical outcomes of conventional in vitro fertilization （IVF） in patients with one retrieved oocyte. Methods ： From January 2013 to January 2015, a to- tal of 256 couples with one retrieved oocyte underwent conventional IVF in our center. According to the rate of MNS, the patients were divided into two groups： MNS 〈 4% （134 cycles） and MNS ≥ 4% （122 cycles）. We compared the rates of no transferrable embryo cycles, fertilization, cleavage, normal fertilization, abnormal fertilization, high-quality embryo and transferrable embryo between the two groups. A total of 75 fresh embryo transfer cycles were performed, 43 in the MNS 〈 4% group and the other 32 in the MNS ≥ 4% group. We also compared the rates of implantation, clinical pregnancy and abortion between the two groups. Results ： There were no statistically significant differences between the two groups in the rates of no transferrable embryo cycles, fertilization, cleavage, nor- mal fertilization, abnormal fertilization, high-quality embryo and transferrable embryo （ P 〉 0.05 ）. The rates of implantation, clinical pregnancy and abortion exhibited no remarkable differences either in the fresh embryo transfer cycles between the two groups （P 〉 0.05 ）. Conclusion ： The rate of MNS does not affect the clinical outcomes of conventional IVF in patients with one retrieved ooeyte.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2016年第2期143-146,共4页
National Journal of Andrology
关键词
正常形态精子百分率
体外受精
单卵
妊娠
morphologically normal sperm
in vitro fertilization
one retrieved oocyte
pregnancy
