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显微开颅夹闭术与血管内栓塞对颅内前循环动脉瘤患者的疗效比较 被引量：22

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摘要 目的:探讨显微开颅夹闭术与血管内栓塞对颅内前循环动脉瘤患者血流动力学及生存质量的影响。方法:颅内前循环动脉瘤患者86例,随机分为栓塞组和夹闭组,夹闭组采用显微开颅夹闭术,栓塞组采用血管内栓塞治疗,采用格拉斯哥预后评分(GOS)评价患者预后,观察术前至术后24 h的血流动力学,SF-36评价患者出院时生活质量,随访24个月,于24个月后采用改良Rankin量表(m RS)和日常生活活动能力(ADL)量表评价生活质量。结果:治疗后栓塞组良好率为93.02%,夹闭组88.37%,2组差异无统计学意义(P>0.05);栓塞组在术中SV、SBP、DBP及HR均低于夹闭组,CI高于夹闭组,差异有统计学意义(P<0.05),术毕SBP、DBP及HR低于夹闭组(P<0.05);出院时,栓塞组在生理功能、总体健康、情感职能以及精神健康方面评分均高于夹闭组(P<0.05);随访24个月发现,夹闭组的m RS评分低于栓塞组(P<0.05),ADL评分和并发症发生率差异无统计学意义(P>0.05)。结论:血管内栓塞术与开颅夹闭术治疗颅内前循环动脉瘤,二者疗效相近,但是血管内栓塞治疗术中患者血流动力学稳定,且出院时患者短期预后优于开颅夹闭术,远期随访患者致残率高于开颅夹闭术。
作者 郭海军 韩德清 陈玉光 黄永凯
机构地区 株洲市中心医院神经外科
出处 《神经损伤与功能重建》 2016年第1期66-68,共3页 Neural Injury and Functional Reconstruction
关键词 显微开颅夹闭术 血管内栓塞 血流动力学 生存质量 颅内前循环动脉瘤
分类号 R741 [医药卫生—神经病学与精神病学] R743 [医药卫生—神经病学与精神病学]
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参考文献14

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二级参考文献43

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共引文献34

同被引文献265

引证文献22

二级引证文献65

神经损伤与功能重建
2016年 第1期

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