期刊文献+

老年轻度认知功能障碍与同型半胱氨酸 血脂的相关性分析 被引量:5

下载PDF
导出
摘要 轻度认知功能障碍(mild cognitive impairment,MCI)是近年来提出的新概念,介于正常衰老与极早期痴呆间的一种以认知功能损害为主要特征的中间状态。随着社会老龄化,老年人的发病率明显高于年轻人。研究表明,MCI患者进展为痴呆的发病率为正常人的10倍,故MCI人群将成为痴呆的高危人群,但存在异质性-([1])。心脑血管损害的重要危险因素之一的高同型半胱氨酸血症已被广泛认可。多数学者认为高同型半胱氨酸血症是痴呆的危险因素之一。
出处 《中国实用神经疾病杂志》 2016年第2期103-104,共2页 Chinese Journal of Practical Nervous Diseases
  • 相关文献

参考文献8

  • 1王鲁宁.老年人轻度认知功能障碍的研究进展[J].中华保健医学杂志,2009,11(4):251-253. 被引量:24
  • 2Mccully KS. Vascular pathology of homoc ysteinemia: impli cations {or the pathogenesis of arteriosclerosis [J]. Am J Pathol,1969,56(1) :111-128.
  • 3中国痴呆与认知障碍诊治指南:轻度认知障碍的诊断和治疗[J].中华医学杂志,2010,90(41):2887-2893. 被引量:183
  • 4Petesen RC,Dwdy R,Kurz A,et al. Current concepts in mild cognitive impairment [J]. Arch Neurol, 2001,58 ( 12 ) : 1 985- 1 992.
  • 5Hanninen T, Hallikainen M, Tuomainen S, et al. Prevalence of mild cognitiveimpairment: a population based study in elderly subjects[J]. Acta Neurol Scand, 2002,106(3) : 148-154.
  • 6赵海云,王艳芳.脑梗死患者轻度认知功能障碍与同型半胱氨酸的关系[J].中国实用神经疾病杂志,2013,16(17):1-3. 被引量:6
  • 7Cutler RG, Kelly J, Storie K, et al. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol me- tabolism in brain aging and Alzheimer's disease[J]. Proc Natl Acad Sci U S A,2004,101(7) 2 070-2 075.
  • 8Farr SA, Yamada KA, Butterfield DA, et al. Obesity and hy pertriglyceridemia produce cognitive impairment[J]. Endocri- nology,2008,149(5) =2 628-2 636.

二级参考文献12

  • 1廖小平,文国强,陈涛,龙志刚,欧阳锋,李天炼,王冰雁.急性脑梗死患者认知功能障碍与病灶部位的相关性研究[J].中风与神经疾病杂志,2007,24(1):71-72. 被引量:49
  • 2Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment :clinical characterization and outcome[J ]. Arch Neurol, 1999, 56 : 303-308.
  • 3Tierney MC, Szalai JP, Snow WG, et al. Prediction of probable Alzheimer's disease in memory-impaired patients:a prospective longitudinal study[J]. Neurology, 1996,46:661-665.
  • 4Bowen J,Teri L, Kukull W, et al. Progression to dementia in patients with isolated memory loss [ J ]. Lancet, 1997,349 : 763-765.
  • 5Graham JE, Rockwood K, Beattie BL,et al. Prevalence and severity of cognitive impairment with and without dementia in an elderly population[J]. Lancet, 1997,349 : 1793-1796.
  • 6Mufson E J, Chen EY, Cochran E J, et al. Entorhinal cortex β-amyloid load in individuals with mild cognitive impairment[J]. Exp Neurol, 1999,158 : 469--490.
  • 7Petersen RC. Culrent concepts in mild cognitiveimpairment[J].Archives of Neurology,2001,(12):1985-1992.doi:10.1001/archneur.58.12.1985.
  • 8Ravaglia G,Forti P,Maioli F. Homocysteine and cognitive function in healthy elderly community dwellers in Italy[J].Clinical Nutrition,2003.668-673.
  • 9Schafer JH,Glass TA,Bolla KI. Homocysteine andcognitive function in a population-based study of older adults[J].Journal of the American Geriatrics Society,2005,(03):381-388.
  • 10Mineur YS,Belzung C,Crusio WE. Effects of unpredictable chronic m ild stress on anxiety and depression-like behavior in mice[J].Behavioural Brain Research,2006,(01):43-50.

共引文献209

同被引文献66

引证文献5

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部