摘要
目的:评价依托孕烯埋植剂避孕的有效性、阴道出血模式、副作用、安全性及可接受性;方法:选择采用依托孕烯埋植剂避孕的妇女150例为研究对象,月经期或人工流产术后植入埋植剂,术后1、3、6、12个月随访,记录其临床症状、副作用、阴道出血情况及取出原因。结果:150例妇女植入依托孕烯埋植剂12个月内无一例妊娠。出血模式主要表现为出血类型的异常,即闭经(32.4%)、出血稀发(23.1%)、出血延长(10.2%)、出血频发(5.6%)。除出血改变外,其他主要表现为体重增加、痤疮、乳房胀痛、卵巢囊肿等。埋植剂续用率为72.0/百妇女年。结论:依托孕烯埋植剂避孕效果好,无重大不良反应发生,安全性好。出血模式的改变和体重增加是其主要副作用,也是影响续用率的主要原因。
Objective：To estimate the contraceptive efficacy,bleeding patterns,side effects,safety and acceptability of the etonogestrel implant.Methods：Form May to December 2013,women who requirement of contraception at family planning in Women＇s Hospital School of Medicine Zhejiang University,150 healthy women received the etonogestrel implants insertion immediately postabortion or menstrual placement.At 1,3,6,12 months follow up,a questionnaire was used to investigate the clinical symptoms,bleeding patterns,side effects,satisfaction,and the reasons for discontinuation of the included patients.Results：Pregnancy rate was 0 in the 150 patients at 12 mouths follow up.The bleeding patterns were abnormal uterine bleeding,which included amenorrhoea（32.4%）,infrequent（23.1%）,frequent（10.2%）,and/or prolonged bleeding（5.6%）.Other reported side effects included weight gain,acne,breast tenderness and ovarian cyst.The continuation rate at the end of 12 months was 72.0/ every hundred women years.Conclusion：Etonogestrel subdermal contraceptive implant has high efficacy with good safety and hasn＇t heavy side effects.The bleeding patterns and weight gain are not only the major side effects,but also are the main reasons for discontinuation.
出处
《中国计划生育学杂志》
2016年第1期28-32,共5页
Chinese Journal of Family Planning
