摘要
目的了解黄埔区出生缺陷重大疾病发生情况,分析发生出生缺陷的高危因素,为预防出生缺陷的发生提供可靠的科学依据。方法收集2012-2014年参加黄埔区出生缺陷筛查的50例经诊断为畸形胎儿的家庭信息为研究组,收集2012-2014年参加黄埔区出生缺陷筛查的50例未发现重大畸形的儿童家庭信息为对照组。结果根据收集调查资料信息分析发现年龄、不良嗜好、是否计划妊娠以及物理、化学因素影响为黄埔区出生缺陷重大畸形疾病的高危因素。而在出生缺陷重大畸形疾病发生中的不同类型的发生率为:死胎(因重大畸形引起)16例,占32%,最高,其次为先天性心脏病13例(26%),再次为唇腭裂8例(16%),第四为多指3例(6%)。结论加强优生优育宣传力度,提高育龄妇女的保健意识,避免环境因素影响,制定完善的出生缺陷一级预防干预策略,加强孕期的胎儿畸形筛查,加强二级干预措施。多方面采取措施,预防出生缺陷的发生。
Objective Learn Huangpu District incidence of major diseases,birth defects,analyze risk factors for the occurrence of birth defects,providing reliable scientific basis for the prevention of birth defects from occurring. Methods Huangpu District to participate in the collection 2012- 2014 screening of birth defects diagnosed 50 cases of fetal malformation family information for the study group,collected 2012- 2014 participate in Huangpu District 50 cases of birth defects screening found no major malformations Child and Family Information for the control group. Results According to information collected by the survey data analysis showed that age,bad habits,whether planned pregnancy and the physical and chemical factors that affect risk factors for birth defects Huangpu major malformations of the disease. Birth defects in major malformations occur in different types of disease incidence： stillbirth（ because major malformations caused by） 16 cases,accounting for 32%,the highest,followed by 13 cases of congenital heart disease,accounting for 26%,again as cleft lip and palate 8 cases,accounting for 16% in the fourth for the multi-finger three cases,accounting for 6%. Conclusion Strengthen eugenics propaganda efforts to improve women＇s reproductive health awareness,avoid the influence of environmental factors,the development of improved intervention strategies for primary prevention of birth defects,fetal malformation during pregnancy to strengthen screening,strengthen secondary interventions. Many take measures to prevent the occurrence of birth defects.
出处
《临床合理用药杂志》
2016年第2期15-16,23,共3页
Chinese Journal of Clinical Rational Drug Use
基金
广东省人口和计划生育委员会科研项目"黄埔区重大体表脏器畸形疾病相关致病因素调查及对照研究"(No:2012227)
关键词
出生缺陷
重大畸形
高危因素
环境因素
Birth defects
Major malformations
Risk factors
Environmental factors
