摘要
目的探讨药物洗脱支架(DES)术后发生支架内血栓(ST)的老年患者临床特点与预后。方法入选经冠状动脉造影证实的DES术后发生ST患者132例,分为老年组(年龄≥60岁)64例和对照组(年龄<60岁)68例。收集患者的临床资料,分析DES术后发生ST的老年患者临床特点与预后。结果老年组住院期间主要不良心血管事件(MACE)发生率明显高于对照组(15.6%vs 1.5%,P=0.004)。Kaplan-Meier分析显示,老年组估算的无事件生存率明显低于对照组(33.2%vs 44.6%,Plog rank=0.025)。Cox多因素回归分析显示,年龄≥60岁(HR=2.19,P=0.022)和LVEF<50%(HR=2.56,P=0.008)是总MACE的独立预测因素。结论 DES术后发生ST的老年患者近远期预后不良。
Objective To study the clinical characteristics and prognosis of elderly patients with stent thrombosis（ST）after drug eluting stenting（DES）.Methods One hundred and thirty-two angiography-conformed ST patients after DES were divided into≥60years old group（n=64）and〈60years old group（n=68）.Their clinical characteristics and prognosis were analyzed.Results The incidence of major adverse cardiac events（MACE）was significantly higher in ≥60years old group than in 〈60years old group（15.6%vs 1.5%,P=0.004）.Kaplan-Meier analysis showed that the estimated MACE free survival rate was significantly lower in ≥60years old group than in 〈60years old group（33.2%vs 44.6%,Plog rank=0.025）.Cox multivariate regression analysis revealed that age≥60years and LVEF50% were the independent risk factors for MACE in elderly ST patients after DES（HR=2.19,P=0.022;HR=2.56,P=0.008）.Conclusion The short-and long-term prognoses are poor in elderly ST patients after DES.
出处
《中华老年心脑血管病杂志》
CAS
2016年第2期149-152,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
