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膝关节骨关节炎病因与关节软骨磨损的相关性研究 被引量:18

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摘要 膝关节骨性关节炎是中老年人一种常见的退行性疾病,女性多于男性,其发病机制目前的主流观点认为是由于关节软骨磨损所致[1-3]。临床大量病例证实,膝关节疼痛程度与关节软骨磨损呈正相关。人们就误以为是由于软骨磨损导致了骨关节炎一系列的临床表现。 Cartilage defect is traditionally recognized as one of the most important etiological factors of knee osteoarthritis(KOA). Based upon the theory of "non-uniform settlement of knee joint", we found that osteoporosis is the most important KOA etiological factor which induces non-uniform settlement. Cartilage damage is only a phenomenon of the KOA, which has no relationship of the periarticular pain and functional disorder
出处 《河北医科大学学报》 CAS 2016年第2期227-229,共3页 Journal of Hebei Medical University
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  • 1Cicuttini F, Ding C, Wluka A, et al, Jones G. Association of cartilage defects with loss of knee cartilage in healthy,middle- age aduhs: a prospective studyLJ]. Arthritis Rheum, 2005,52 (7) : 2033-2039.
  • 2Ding C,C;icuttini F,Seott F,et al. Association of prevalent and incident knee cartilage defects with loss of tibial and patellarcartilage:a longitudinal studyEJ~. Arthritis Rheum, 2005, 52 (12) :?,918-3927.
  • 3Wluka AE, Dins C,Jones G, et al. The clinical correlates of articular cartilage defects in symptomatic knee osteoarthritis: a prospective study~J~. Rheumatology (Oxford), 2005,44 ( 10 ) : 1311-1316.
  • 4Jones G, Dins C, Scott F, et al. Early radiographic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both males and females[J]. Osteoarthritis Cartilage, 2004,12(2) .. 169 - 174.
  • 5秦迪,陈伟,吕红芝,董天华,郑诚功,张英泽.腓骨中上段部分切除治疗膝关节内侧间室骨性关节炎机制研究及治疗效果影响因素分析[J].河北医科大学学报,2015,36(6):727-729. 被引量:33
  • 6陈伟,秦迪,吴涛,张飞,陈启明,张英泽.应用腓骨截骨术治疗膝关节骨性关节炎效果优良的机制分析[J].河北医科大学学报,2015,36(6):726-727. 被引量:79

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