摘要
目的：研究血清低密度脂蛋白胆固醇（LDL-C冰平与跟腱厚度（ATT）之间的相关陛。方法：2014-03至2015—03期间收集18。75岁、血清LDL—C水平高于正常上限（≥3．37mmol/L）的患者154例，根据《中国成人血脂异常防治指南（2007年）》，分为LDL—C边缘升高（3．37～4．12mmol／L）組（n=50）和LDL—C升高（≥4．14mmol／L）组（n=104）；另以血清LDL—C水平正常（〈3．37mmol／L）者作为对照组（n=51）。采用标准化的直接数字化X线摄影术测量三组受试者的ATT，进行比较，并分析血清LDL—C水平与ATT之间的相关性。结果：LDL—C升高组的ATT平均值[（9．42±3．63）mm]高于LDL—C边缘升高组[（8．24±1．73）mm]和对照组[（6．05±0．28）mm]，三组受试者ATT间的差异均具有统计学意义（P均〈0．05）。线性相关分析显示，血清LDL—C水平与ATT平均值的相关系数r=0．346（P〈0．001）。结论：本研究小样本初步观察发现，血清LDL—C水平越高，ATT越厚，血清LDL—C水平与ATT呈正相关，该现象及其意义有待大样本多中心研究进一步证实。
Objective： To analyze the relationship between the serum levels of low density lipoprotein cholesterol （LDL-C） and achilles tendon thickness （ATT）. Methods： We studied 154 patients with high serum level of LDL-C （LDL-C 〉 3.37 mmol/L） from 2014-03 to 2015- 03, the patients were at （18-75） years of age. According to （（Guidelines on Prevention and Treatment of Blood Lipid Abnormality in Chinese Adults 2007）） , the patients were divided into 2 groups： Borderline high LDL-C （3.3-4.12 mmol/L） group n=50 and High LDL-C （〉4.14 mmol/L） group, n=104; in addition, there was a Normal control group （LDL-C 〈3.37 mmol/L）, n=51. ATT values were measured by standard digital radiography and the results were compared among 3 groups; the relationship between serum levels of LDL-C and ATT was studied. Results： ATT levels in High LDL-C group （9.42 ±3.63） mm was higher than Borderline high group （8.24±1.73） mm and Normal control group （6.05±0.28）mm, all P〈0.05. The liner correlation coefficient of serum level of LDL-C and the mean ATT was （r=0.346, P〈0.001）. Conclusion： Our preliminary research showed that the higher serum level of LDL-C associated with thicker ATT, they had positive correlation. This phenomenon should be further confirmed by large sample and multi-center investigation.
出处
《中国循环杂志》
CSCD
北大核心
2016年第2期132-136,共5页
Chinese Circulation Journal
基金
海南省医药卫生科研项目(1421320.24A1005)
关键词
脂蛋白类
LDL
跟腱
黄瘤病
放射摄影术
Lipoproteins, LDL
Achilles tendon
Xanthomatosis
Radiography
