非酒精性脂肪性肝病与高尿酸血症相互关系的研究现状及展望被引量：4

Studies on association between nonalcoholic fatty liver disease and hyperuricemia： current status and future prospects

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摘要尿酸是机体嘌呤代谢的终末产物,尿酸水平升高显著增加痛风、心血管疾病、2型糖尿病等疾病发病风险.近年来的研究表明,高尿酸血症与非酒精性脂肪性肝病（NAFLD）关系密切.本文结合笔者所在课题组近年来研究结果,就高尿酸血症与NAFLD相互关系及其机制研究进展作一概述. Uric acid is the end-product of purine metabolism.It has been widely accepted that the increase in the level of uric acid significantly raises the risks of gout,cardiovascular disease,and type 2 diabetes.The studies in recent years have shown that hyperuricemia is closed related to nonalcoholic fatty liver disease （NAFLD）.This review summarizes the research advances in the association between hyperuricemia and NAFLD and related mechanisms based on the author＇s recent research findings.

作者厉有名

机构地区浙江大学医学院附属第一医院消化内科

出处《中华肝脏病杂志》 CAS CSCD 北大核心 2016年第2期89-91,共3页 Chinese Journal of Hepatology

基金国家973计划（2012CB524905）、国家科技支撑计划（2012BAI06B04）、国家自然科学基金（81170378,81100278）

关键词高尿酸血症黄嘌呤氧化酶非酒精性脂肪性肝病 Hyperuricemia Xanthine oxidase Non-alcoholic fatty liver disease

分类号 R575 [医药卫生—消化系统]

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