摘要
目的 探讨血清前列腺特异性抗原（PSA）检测预测良性前列腺增生（BPH）并发急性尿潴留（AUR）的应用价值,为BPH并发AUR的临床治疗和预后提供参考.方法 选取本院2013年1月～ 2014年12月收治住院治疗的289例BPH患者的临床资料,其中并发AUR者183例（AUR组）,未并发AUR者106例（非AUR组）.比较两组患者总血清前列腺特异性抗原（tPSA）、tPSA/年龄、前列腺体积（PV）及PSA密度（PSAD）水平的差异;分析两组患者不同tP-SA、PV及PSAD水平的分布率.结果 AUR组tPSA、tPSA/年龄、PV及PSAD均大于非AUR组,两组比较差异均有显著性统计学意义（P＜0.01）.Sperman＆#39;s相关性分析表明,tPSA、tP-SA/年龄及PSAD间存在正相关性（r=0.921,P＜0.05）;tPSA与PV间呈正相关性（r=0.920,P ＜0.05）.随着tPSA、PV及PSAD水平的逐渐增加,AUR的发生率逐渐升高.结论 PSA的检测可作为BPH并发AUR的预测指标,值得临床推广应用.临床检测中应结合tPSA/年龄、PV及PSAD等结果综合考虑.
Objectives To investigate the predictive value of the detection of serum prostate specific antigen （PSA） for benign prostatic hyperplasia （BPH） with acute urinary retention （AUR）, provide the reference for the clinical treatment and prognosis of BPH complicated with AUR.Methods 289 cases patients with BPH in our hospital from 2013 January to 2014 December were chosen and divided into AUR group （n =183） and non AUR group （n =106）.The total serum prostate-specific antigen （tPSA）, tPSA/age, prostate volume （PV） and the density of PSA （PSAD） level difference of the two groups were compared.And the distribution rate of tPSA, tPSA/age , PV and PSAD of the two groups were studied.Results The tPSA, tPSA/age, PV and PSAD of the AUR group were all lesser than those in the non AUR group（P 〈0.01）.Sperman＆#39;s related research shows that, there was positive correlation between age and tPSA, tPSA/PSAD （r =0.921, P 〈 0.05）;tPSA and PV were also positively correlated （r =0.920, P 〈 0.05）.With the gradual increase of tPSA, PV and PSAD levels, the incidence of AUR increased gradually.Conclusions The detection of PSA can be used as a predictor of BPH complicated with AUR, and it is worthy of clinical application.The tPSA/age, PV and PSAD should be considered for the results of clinical detection.
出处
《国际泌尿系统杂志》
2016年第1期100-102,共3页
International Journal of Urology and Nephrology
