摘要
目的:探讨行为激活疗法合并艾司西酞普兰治疗抑郁障碍患者的疗效。方法:将62例抑郁症患者随机分为研究组和对照组,每组各31例。研究组患者给予行为激活疗法合并艾司西酞普兰治疗;对照组患者单用艾司西酞普兰治疗。分别于治疗前、治疗后以及1年随访时,以HAMD评定两组患者的疗效,以GQOLI-74评定其生活质量,以服药情况评定其治疗的依从性。结果:研究组患者的HAMD减分率和生活质量明显好于对照组(P<0.05)。1年随访前者依从性明显高于后者(P<0.05),前者复发率明显低于后者(P<0.05)。结论:研究组患者的疗效及依从性高于对照组,且远期疗效和预防复发作用好。
Objective:To explore efficacy of behavioral activation therapy combined with Escitalopram in treatment of depres-sion. Methods:62 patients diagnosed as depression were divided into study group ( behavioral activation combined with Escitalopram therapy group) and control group ( Escitalopram therapy group) with 31 cases in each group by random. Hamilton depression scale (HAMD) was used to evaluate efficacy, general quality of life inventory-74 (GQOLI-74) was used to evaluate quality of life, and medication was used to evaluate the patients' compliance. Results:The total scores of HAMD reduced and the scores of GQOLI-74 in-creased of study group were better than those of control group significantly (P<0. 05). After 1 year follow-up, the compliance for stud-y group was much higher than that of control group significantly (P<0. 05), but the rate of the recurrence of study group was lower than that of control group significantly (P<0. 05). Conclusions:Behavioral activation combined with Escitalopram therapy compared with Escitalopram therapy can improve the efficacy and compliance significantly, and has a good long-term effectiveness and prevention of recurrence.
出处
《中国民康医学》
2016年第2期7-9,共3页
Medical Journal of Chinese People’s Health