摘要
目的探讨HFMD患儿早期检测血清炎症因子及免疫因子的临床意义。方法将2014年8月~2015年8月收治的90例HFMD患儿分为普通组49例,重症组41例,另选同期至本院体检的50例健康儿童纳入对照组。检测三组各项炎症及免疫指标。结果普通组和重症组WBC、CRP、PCT水平均显著高于对照组,而重症组均显著高于普通组。普通组和重症组Ig A、Ig G、Ig M水平均显著低于对照组,而三组间C3和C4水平无显著差异,重症组Ig A、Ig G、Ig M水平均显著低于普通组、重症组CD3^+、CD4^+、CD8^+、CD4^+/CD8^+水平均显著低于对照组。结论发病早期联合检测WBC、CRP、PCT、免疫球蛋白和外周血T细胞亚群对手足口病的诊断、病情判断具有重要的临床意义。
Objective To investigate the clinical significance of early detection serum inflammatory factors and immune factors in children with HFMD. Methods From August 2014 to August 2015,90 cases of HFMD were divided into ordinary group（49 cases） and severe group（41 cases）,and selected 50 healthy children as the control group. The inflammation and immunity index were compared. Results The levels of PCT,CRP and WBC in the normal group and the severe group were significantly higher than those in the control group,while the severe group was significantly higher than those in the normal group. The levels of Ig G,Ig M and Ig A in normal group and severe group were significantly lower than those in control group,but there was no significant difference in C3,C4. The Ig G,Ig M and Ig A levels of severe group were significantly lower than those in normal group,CD3^＋,CD4^＋,CD8^＋,CD4^＋/CD8^＋in severe group were significantly lower than that in control group. Conclusion Early detection of WBC,CRP,PCT, immunoglobulin and peripheral blood T lymphocyte subsets in the diagnosis and disease diagnosis has important clinical significance.
出处
《中国现代医生》
2016年第2期55-57,共3页
China Modern Doctor
关键词
手足口病
肠道病毒
炎症因子
免疫因子
Hand foot mouth disease
Intestinal virus
Inflammatory factor
Immune factor
