摘要
目的探讨急性大面积肺血栓栓塞症心肌肌钙蛋白Ⅰ的临床表达水平及其意义.方法：采用回顾性分析法,选取2013年2月～2014年8月我院接受治疗的120例肺血栓栓塞症患者的临床资料,按照患者是否伴有急性大面积的肺血栓将120例患者分为两组,伴有急性大面积肺血栓患者为观察组,未伴有急性大面积肺血栓患者为对照组,每组各60例患者.利用全自动生化仪、超声仪等检测患者血清心肌酶、血浆心肌肌钙蛋白I浓度、肺动脉收缩压、血气情况等,并分析急性大面积肺血栓栓塞症患者血浆中心肌肌钙蛋白Ⅰ在不同时间段平均检测值的价值.结果：经过检测与分析,发现对照组患者心肌肌钙蛋白Ⅰ测定值、右心功能不全、血气分析、症状及预后结果均明显优于观察组,经统计学比较,P〈0.05,具有统计学意义;而且观察组患者发生心源性休克和死亡率明显高于对照组,经统计学比较,P〈0.05,具有统计学意义;对观察组患者进行心肌肌钙蛋白Ⅰ监测,发现5h后患者出现阳性反应,20h后患者的阳性值达到峰值.结论：急性大面积肺血栓栓塞症患者的心肌肌钙蛋白Ⅰ水平明显升高,可以作为判断病变的指标,有利于病情危险分层,提高患者预后生活质量.
Objective: To investigate the acute massive pulmonary thromboembolism clinical expression of cardiac troponin I levels and its significance.Methods:A retrospective analysis, selection in February 2013 to August 2014, our hospital for treatment of the clinical data of 120 patients with pulmonary thromboembolism, according to whether the patients with acute massive pulmonary embolism of 120 patients were divided into two groups, with as the observation group, patients with acute massive pulmonary embolism was associated with acute massive pulmonary embolism patients as control group, each group of 60 cases each.Using automatic biochemistry analyzer, ultrasonic instrument detection such as patients' serum myocardial enzyme, concentration of serum cardiac troponin I, pulmonary artery systolic blood pressure, blood gas, etc., and analysis in patients with acute massive pulmonary thromboembolism plasma cardiac troponin I in different times the value of the average values. Results:Through testing and analysis, found that in the control group in patients with myocardial troponin I measurements, right cardiac insufficiency, blood gas analysis, symptoms and prognosis results were significantly better than the observation group, the statistical comparison,P<0.05, there was statistical significance; And observation group of patients with cardiac shock and mortality is significantly higher than the control group, by statistical comparison,P<0.05, there was statistical significance; The observation group of patients with cardiac troponin I monitoring, found that patients with positive reaction after 5 h, peak after 20 h in patients with positive values.Conclusion:Patients with acute massive pulmonary thromboembolism myocardial troponin I level increased significantly, it is use as a judge index of lesions, is helpful for disease risk stratification, improve the prognosis of patients quality of life.
出处
《中国医药导刊》
2016年第2期125-126,129,共3页
Chinese Journal of Medicinal Guide
关键词
急性
大面积肺血栓栓塞症
心肌肌钙蛋白I
临床表达水平
意义
Acute
Large area of pulmonary thromboembolism
Myocardial troponin I
Clinical expression level
Meaning
