摘要
目的探讨丁苯酞软胶囊联合血栓通注射液对脑梗死急性期患者神经功能恢复的临床疗效及安全性。方法选择2012年1月—2014年7月收治的100例急性脑梗死患者作为研究对象,随机分为对照组和治疗组各50例。对照组给予常规治疗,试验组在对照组的基础上加用丁苯酞软胶囊联合血栓通注射液,疗程为30 d。观察两组患者治疗前及治疗后14、30 d国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分及日常生活活动Barthel指数得分情况。计量资料组间比较采用t检验,组内比较采用配对t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果试验组治疗后14、30 d NIHSS得分分别为(3.37±3.03)、(2.48±1.05)分,均低于治疗前的(6.00±3.30)分,差异均有统计学意义(均P<0.05)。治疗后14、30 d,试验组NIHSS得分均低于对照组的(5.65±4.00)、(3.00±1.43)分,差异均有统计学意义(均P<0.05)。试验组治疗后14、30 d Barthel指数分别为(78.56±20.16)、(85.21±15.28)分,均低于治疗前的(65.38±27.98)分,差异均有统计学意义(均P<0.05)。治疗后14、30 d,试验组Barthel指数均低于对照组的(70.05±20.75)、(78.52±16.37)分,差异均有统计学意义(均P<0.05)。试验组总有效率为94%,高于对照组的72%,差异有统计学意义(P<0.05)。结论丁苯酞软胶囊联合血栓通对脑梗死急性期患者神经功能恢复具有显著的促进作用,临床疗效安全可靠,值得进一步推广应用。
Objective To investigate the chnical efficacy of Butylphthalide Soft Capsules and Xueshuantong in the treatment of acute cerebral infarction.Methods 100 patients of acute cerebral infarction from January 2012 to July 2014 were selected and randomly divided into control group and treatment group （n=50）.The patients in control group received conventional therapy;the patients in treatment group were treated with Xueshuantong and Butylphthalide Soft Capsules,the two groups all treated for 30 days.The national institute of health stroke scale（NIHSS） and Barthel index of the two groups before and after treatment 14,30 d were recorded and compared.Measurement data between groups was processed by t test,in groups was processed by paired t test, count data was processed by chi square test,P〈0.05 was considered statistically significant.Results 14 and 30 days after treatment,the NIHSS score of treatment group were （3.37 ± 3.03）,（2.48 ± 1.05）points,lower than that before treatmenl [（6.00 ± 3.30） points],the differences were statistically significant（all P〈0.05）,14 and 30 days after treatment,the NIHSS score of treatment group were lower than that of the control group [（5.65 ± 4.00）,（3.00 ± 1.43）points],the differences were statistically significant（allP〈0.05）. 14 and 30 days after treatment,the Barthel index of treatment group were （78.56 ± 20.16）,（85.21 ± 15.28）points,lower than that before treatment [（65.38 ± 27.98）points],the differences were statistically significant （all P〈0.05）.14 and 30 days after treatment,the Barthel index of treatment group were lower than that of the control group [（70.05± 20.75）,（78.52 ± 16.37）points],the differences were stati- stically significant（all p〈0.05）.The total effective rate of treatment group was 94%,higher than that of the control group （72%）,the difference was statistically significant different（P〈0.05）.Conclusion Treatment of Butylphthalide Soft Capsules and Xueshuantong to patients with acute cerebral infarction has a significant role in promoting the clinical efficacy of safe,reliable,worthy of further application.
出处
《社区医学杂志》
2016年第3期26-29,共4页
Journal Of Community Medicine
关键词
丁苯酞胶囊
血栓通
脑梗死
神经功能缺损程度评分
BARTHEL指数
Butylphthalide Soft Capsules
Xueshuantong
Aeule cerebral infarction
National institute of health s｜roke scale
Barthelindex
