摘要
目的:观察苏黄止咳胶囊联合孟鲁司特治疗上呼吸道感染后咳嗽的临床效果。方法:确诊上呼吸道感染后咳嗽患者120例随机分为观察组(64例)和对照组(56例)。对照组患者口服孟鲁司特咀嚼片10 mg,po,qn,观察组患者在对照组基础上加用苏黄止咳胶囊1.35 g,po,tid,疗程2周。比较两组患者的疗效和药品不良反应。结果:观察组患者的显效率、总有效率均明显高于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者的咳嗽症状评分和咯痰症状评分均较治疗前明显下降(P<0.05),且观察组两项评分均明显低于对照组治疗后(P<0.05)。两组药品不良反应发生率差异无统计学意义(P>0.05)。结论:苏黄止咳胶囊联合孟鲁司特治疗呼吸道感染后咳嗽的临床效果明显优于单用孟鲁司特,安全有效,值得在临床上进行推广。
Objective： To evaluate the clinical efficacy of Suhuang Zhike capsules combined with montelukast in the treatment of cough caused by upper respiratory infection. Methods： Totally 120 patients with cough after upper respiratory infection were randomly divided into the treatment group （64 cases） and the control group （ 56 cases） by the random number table. The control group received Montetukast chewable tablets alone（ 10 mg,po qn）, while the treatment group received Suhaung Zhike capsules（ 1.35 g,po,tid） com- bined with Montelukast chewable tablets. The treatment course was 2 weeks, and the efficacy and adverse reactions between the two groups after the treatment were compared. Results： The significant efficiency and the total efficiency of the observation group were significantly highter than those of the control group, and the difference was statistically significant（ P 〈 0.05 ）. After the treatment, the cough symptom score and the expectoration symptom score of the two groups were decreased significantly than those before the treatment （P 〈 0.05 ）, both scores of the observation group were significantly lower than those of the control group after the treatment （ P 〉 0.05 ）. The incidence of adverse reactions of the two groups had no significant differencet（ P 〈 0.05 ）. Conclusion： As for the clinic efficacy, the combination of Suhaung Zhike capsules and Montelukast is significantly better than Montelukast therapy, and the combina- tion is an effective and safe treatment for cough after upper respiratory infection and worthy of promotion in clinical practice.
出处
《中国药师》
CAS
2016年第2期332-334,共3页
China Pharmacist
关键词
苏黄止咳胶囊
孟鲁司特
上呼吸道感染后咳嗽
Suhuang Zhike capsules
Montelukast
Cough after upper respiratory infection
