摘要
目的探讨规范Ⅰ类切口手术预防使用抗菌药物的方法,为规范使用抗菌药物提供参考。方法回顾性调查某院药师干预前（2010年6月至8月）与药师干预后（2011年6月至8月）各100例Ⅰ类切口手术患者病历资料,统计评价及对比分析2次调查的围手术期抗菌药物预防使用率、品种选择、给药时机、住院时间、住院时间等。结果干预前100例患者全部预防性应用了抗菌药物,预防性用药率为100.00%;术前0.5～2 h用药78例（78.00%）,术前2～24 h用药14例（14.00%）,术后用药8例（8.00%）,预防围手术期感染的用药疗程合理8例（8.00%）,平均抗菌药物总费用为934.7元,平均住院总费用为7 083.1元,人均住院时间为295.2 h。干预后,100例患者中有16例（16.00%）使用抗菌药物,术前0.5～2 h用药100例（100.00%）,无术后用药,预防围手术期感染的用药疗程合理为100例（100.00%）,平均抗菌药物费用为2.0元,平均住院费用为4 671.4元,人均住院时间为162.2 h,感染率与干预前相比差异无统计学意义。结论药师干预Ⅰ类切口手术预防使用抗菌药物后,可有效提高合理用药水平。
Objective To explore the standard method of perioperative prophylactic antibiotics applied to Type I incision so as to pro- vide the reasonable use of antibiotics. Methods The medical records of 100 cases collected before the intervention （from June of 2010 to Aug of 2010）with those of 100 cases after the intervention （from June 2011 to August 2011） were compared. Results Of the total 100 cases collected before intervention, all （100.00%） received antibiotics, with 78 cases （78.00%） receiving antibiotics 0.5-2 h before operation, 14 cases （14.00%） 2-24 h before operation, and 8 cases （8.00%） after operation. Postoperatively, the rational ratio of course of antibiotic treatment was 8 eases（8.00% ）, the mean cost of antibiotics was 934.7 Yuan, and the mean hospitalization cost was 7 083. 1 Yuan. The average hospitalization time was 295.2 h. Of the 100 cases after intervention, 16 cases （16.00%） were given antibiotics, with 100 cases （100. 00% ） receiving antibiotics 0.5 - 2 h before operation and 0 cases （0. 00% ） after operation; postopera- tively, the rational ratio of course of antibiotic treatment was 100 cases（100.00% ）. the mean cost of antibiotics was 2. 0 Yuan, and the mean hospitalization cost was 4 671.4 Yuan. The average hospitalization time was 162. 2 h. The infection rate showed no statistical dif- ference before and after intervention. Conclusion The intervention of pharmacist to the prophylactic antibiotic application can apparently improve the level of rational drug use during peroperative period.
出处
《中国药业》
CAS
2016年第3期57-60,共4页
China Pharmaceuticals
基金
2014年四川省教育厅资助课题
项目编号:SJWF1401
关键词
药师
Ⅰ类切口
合理用药
抗菌药物
pharmacist
type I incision
rational drug use
antibiotics
