摘要
目的了解医院药品不良反应发生的规律及相关因素,为临床合理用药提供参考。方法对北京朝阳医院2014年266例药品不良反应报告进行归类统计、评价。结果 266例药品不良反应报告中,患者男性多于女性,比例为1∶0.8,60岁以上老年患者发生不良反应为115例(43.23%)。抗菌药物不良反应发生率最高,其次为抗肿瘤药物。给药途径以静脉滴注为主,不良反应的临床表现以皮肤及其附件损害为主,其次为消化系统、血液系统及全身性损害,分别为31.20%,30.83%,9.77%,9.77%,严重不良反应15例(5.64%)。结论应进一步加强药品不良反应监测情况,加大药品不良反应宣传力度,重视抗菌药物及抗肿瘤药物的不良反应监测,以免发生严重不良反应。
Objective To understand the law of hospital adverse drug reactions and related factors, to provide reference for clinical ratio- nal drug use. Methods 266 cases of adverse drug reaction reports in The Beijing Chaoyang Hospital in 2014 were statistically classi- fied and evaluated. Results In the 266 cases of adverse drug reactions, there were more men than women, the ratio was 1：0.8; l l5 cases of adverse reactions were patients over the age of 60 （43.23%）. The antimicrobial＇s incidence of adverse drug reactions was the highest, followed by anticancer drugs. The main route of administration was by intravenous infusion, the clinical manifestations of adverse reactions was skin and its appendages, followed by the digestive system, blood system and body damage, accounted for 31.20%, 30.83%, 9.77%, 9.77% respectively; serious adverse reactions 15 cases （5.64%）. Conclusion It is necessary to further strengthen the monitoring of adverse drug reactions, increase publicity efforts on adverse drug reactions, pay more attention to the monitoring of ad- verse reactions of antibiotics and anticancer drugs, in order to avoid the occurrence of serious adverse reactions.
出处
《中国药业》
CAS
2016年第3期84-86,共3页
China Pharmaceuticals
关键词
药品不良反应
药品不良反应监测
合理用药
adverse drug reactions
adverse drug reactions monitoring
rational drug use
