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卡培他滨致手足综合征的护理研究进展 被引量:21

Research progress on nursing care of patients with hand-foot syndrome caused by capecitabine
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摘要 卡培他滨(希罗达),化学名称为胸腺嘧啶磷酸化酶激活的氟尿嘧啶,是一种新型的口服抗肿瘤的细胞毒药物。因其高效、低毒的特点且方便口服的给药方式,越来越广泛地应用于结直肠癌、胃癌、卵巢癌及晚期乳腺癌的治疗,但手足综合征(hand-foot syndrome,HFS)是其最常见的治疗相关的不良事件,即出现以掌跖部感觉丧失及红斑为主的特异性皮肤综合征,表现为手足色素沉着、皮肤肿胀、水疱、溃疡伴疼痛,严重者影响到日常生活,其总发生率高达45%-68%。
出处 《护理研究(下旬版)》 2016年第1期275-278,共4页 Chinese Nursing Researsh
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