摘要
文章初步探索沸石分子筛应用于生物碱富集纯化的可行性,以忽地笑中石蒜碱为吸附对象,以吸附率、洗脱率为指标,考察几种沸石分子筛的使用效果,并与阳离子树脂进行对比,探索沸石分子筛最佳的吸附、洗脱条件。结果表明:ZSM-5沸石分子筛的吸附与洗脱效果相对较好,优于MCM-22、13X分子筛和D001、HD-8阳离子树脂。上样液p H值为4时,ZSM-5沸石分子筛的吸附效果相对较好;以含2.0mol/L氨水的70%的乙醇作为石蒜碱的洗脱剂效果相对较好。
This article made preliminary study on the feasibility of the application of zeolite molecular sieves on enrichment and purification of alkaloid. The effects of different zeolite molecular sieves were examined based on indicators of adsorption rate and elution rate when lycorine in short-tube Lycoris aurea was taken as absorption object. Moreover, a comparison of effect was made with cationic resin to explore the optimal adsorption and elution conditions of zeolite mo- lecular sieve. According to the result, ZSM-5 zeolite molecular sieve had better adsorption and elution effect, which were better than those of MCM-22 or 13X molecular sieve and D001 or HD-8 cationic resin. When pH value of upper sample liquid was 4,the adsorption effect of ZSM-5 zeolite molecular sieve was comparatively better;when 70% ethyl alcohol containing 2.0 mol/L ammonium hydroxide was taken as the eluent of lycorine, the elution effect was comparatively better.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2016年第2期289-292,299,共5页
Natural Product Research and Development
基金
吉首大学引进人员科研资助经费研究项目(jsdxrcyjky xm201302)
关键词
沸石分子筛
石蒜碱
吸附纯化
zeolite molecular sieve
lycorine
absorption and purification
