摘要
目的:观察人工泪液治疗儿童干眼症的疗效及安全性。方法:对58例116眼经泪膜破裂时间(tear break-up time,BUT)、泪液分泌试验(SchirmerⅠtest,SⅠt)、泪河高度、角膜荧光染色、睑板腺功能检查方法确诊为干眼症的儿童患者进行人工泪液治疗,疗程为1mo,复查时再次行上述检查,对各观察指标进行统计分析。结果:儿童干眼症患者58例116眼治疗前BUT为6.03±1.19s,SⅠt为7.67±2.32mm/5min,泪河高度为0.20±0.02mm,角膜荧光染色为1.02±0.13分,睑板腺功能评分为2.45±0.86分。其中31例62眼为脂质缺乏型干眼、20例40眼为水液缺乏型干眼、7例14眼为其他类型。根据其分型,给予相应的人工泪液治疗,治疗1mo后患者的临床症状明显改善,BUT为13.72±1.83s,SⅠt为12.38±3.64mm/5min,泪河高度为0.36±0.08mm,角膜荧光染色为0.03±0.24分,睑板腺功能评分为1.57±0.93分。各观察指标与治疗前相比,差异具有统计学意义(P<0.05)。所有患者在治疗期间均未出现任何不良反应。结论:利用人工泪液治疗儿童干眼是安全、有效的。
AIM：To observe the efficacy and safety of artificial tears for children xerophthalmia.·METHODS：Fifty- eight cases with 116 eyes were diagnosed as xerophthalmia by tear break- up time（BUT）,Schirmer Ⅰ test（S Ⅰt）,tear meniscus height,corneal staining,meibomian gland function test and were given artificial tears therapy for 1mo.Then the aforementioned tests were conducted again for statistical analysis.·RESULTS：The mean BUT of all the children before treatments was 6.03±1.19 s,SⅠt was 7.67±2.32mm/5min,tear meniscus height was 0.20±0.02 mm,corneal staining was 1.02±0.13 scores and meibomian gland function was 2.45±0.86 scores.Sixty-two eyes in 31 cases were the lipid-deficient type,40 eyes in 20 cases were aqueous-deficient type,and 14 eyes in 7 cases were other types.According to their types,corresponding artificial tears therapy was given.At 1mo after treatments,the clinical symptoms were improved significantly.BUT was 13.72±1.83 s,SⅠt was 12.38±3.64mm/5min,tear meniscus height was 0.36±0.08 mm,corneal fluorescein staining was 0.03±0.24 scores and meibomian gland function was 1.57 ± 0.93 scores.Compared with those before treatments,the difference of each observed indicators was statistically significant（P0.05）.No patient experienced any adverse reactions during treatments.·CONCLUSION：Artificial tears treatment for children xerophthalmia is safe and effective.
出处
《国际眼科杂志》
CAS
2016年第3期569-571,共3页
International Eye Science
关键词
儿童
干眼症
人工泪液
children
xerophthalmia
artifical tear
