摘要
目的探讨下咽癌及全喉切除术后咽瘘发生的相关危险因素。方法回顾性分析我院2009年1月至2014年1月收治的78例咽喉癌并行全喉切除术患者的临床资料,并分析咽瘘发生的相关危险因素。结果经单因素分析显示,发生咽瘘患者的术前放疗、术前营养状况及临床分期、感染等与未发生咽瘘者有明显差异(P<0.05);多因素回归分析显示,术前放疗、临床分期、营养状况及感染因素为咽瘘发生的主要危险因素(P<0.05)。结论全喉切除与下咽癌术后并发咽瘘为高发性并发症,术前放疗及临床分期、营养状况、感染是咽瘘发生的主要危险因素,针对危险因素实施有效控制,对预防咽瘘的发生具有一定价值。
Objective To investigate the related risk factors of pharyngeal fistula after total laryngectomy and hypopharyngeal carcinoma surgery. Methods The clinical data of 78 pharyngolaryngeal cancer patients implemented total laryngectomy in our hospital from January 2009 to January 2014 were retrospectively analyzed. The related risk factors of pharyngeal fistula were analyzed. Results According to the single factor analysis, the preoperative radiotherapy, preoperative trophic status, clinical stages and infection of patients suffering from pharyngeal fistulas had significant difference with patients who did not suffer from pharyngeal fistulas（P〈0.05）. According to the multifactor analysis, the preoperative radiotherapy, preoperative trophic status, clinical stages and infection were the main dangerous factors that lead into pharyngeal fistulas（P〈0.05）. Conclusions The incidence of pharyngeal fistulas is high after total laryngectomy and hypopharyngeal carcinoma surgery. The preoperative radiotherapy, preoperative trophic status, clinical stages and infection are the main risk factors that lead into pharyngeal fistulas. Effective control aiming at risk factors has a certain value for preventing the occurrence of pharyngeal fistulas.
出处
《临床医学工程》
2016年第2期255-256,共2页
Clinical Medicine & Engineering
关键词
全喉切除
下咽癌
危险因素
咽瘘
Total laryngectomy
Hypopharyngeal carcinoma
Dangerous factor
Pharyngeal fistula
