摘要
目的:采用注射用奥美拉唑钠作为对照药品,对注射用兰索拉唑治疗消化性溃疡出血的成本-效果进行分析。方法:检索中国生物医学文献数据库(CBM)、中文科技期刊全文数据库(VIP)、中国期刊全文数据库(CNKI)、万方数据库中进行检索、收集相关文献,采用Rev Man4.2软件进行统计分析。结果:兰索拉唑组直接医疗成本比奥美拉唑组低149.85元。兰索拉唑组总有效率高出奥美拉唑2.66个百分点,效果较好,成本较低,具有很好的经济性;兰索拉唑组显效率比奥美拉唑组低3.46个百分点,存在成本较低,效果也较差,是否具有经济性需要进一步评价。结论:以总有效率数据作为效果指标进行分析时,与奥美拉唑组相比,兰索拉唑组效果较好,成本较低,具有很好的经济性。以显效率数据作为效果指标进行分析时,与奥美拉唑组相比,兰索拉唑组仍存在效果略差,存在成本优势。敏感性分析结果也证实了这一结论。
Objective：To study the cost – effectiveness of the injection lansoprazole with omeprazole sodium as control drug in the treatment of digestive ulcer bleeding.Methods：We searched the Chinese biomedical literature database （CBM）, Chinese science and technology periodical full text database （VIP）, Chinese journal full text database （CNKI）, to collect the relevant documents, and use RevMan4.2 for further statistical analysis.Results：lansoprazole group but not omeprazole group had lower direct medical costs （nearly 149.85 yuan decreased）. The totoal effective rate of Lansoprazole group was much higher than the omeprazole group （nearly 2.66 percentage higher than omeprazole）. Our study showed that the effect of lansoprazole is better, and the cost is low, also has good economy; Nevertheless, lansoprazole group showed markedly lower rate of effective rate than omeprazole group, which means that cost is low, the effect is poor. The economy still need further evaluation.Conclusion：Use the total efficiency data as an indicator of effectiveness analysis, lansoprazole group＇s effect is much better, and the cost is low. It showed good economy. However when efficiency data used as an indicator of effectiveness analysis, lansoprazole group still exist slightly worse results, and have a cost disadvantage. The sensitivity analysis results also confirm this conclusion.
出处
《药品评价》
CAS
2015年第24期6-14,36,共10页
Drug Evaluation
