摘要
目的探讨软组织肿瘤手术治疗联合化疗或放疗综合治疗的疗效分析。方法选择2008年至2011年收治的43例软组织肿瘤患者,分析X线、病理学和组织学检查结果以及治疗方法。11例患者采用单纯手术治疗。进行肿瘤的广泛切除:14例患者采用术前放疗+手术切除+术后放疗;9例采用术前顺铂化疗+手术切除+术后顺铂化疗:9例患者术前放疗+手术切除+术后顺铂化疗+术后放疗。结果7例患者肿瘤复发,其中1例足底纤维瘤患者,经过3次复发并广泛切除后截肢治疗。所有患者3年生存率为69.77%.脂肪瘤患者生存率较好,为100.00%。结论术前进行X线、病理学和组织学检查,对于软组织肿瘤治疗方法的选择十分重要。依据患者具体病情选择合适的治疗方法能提高临床疗效,其中术前放疗+手术切除+术后顺铂化疗+术后放疗治疗恶性肿瘤效果较好。
Objective To investigate the efficacy of surgical treatment of soft tissue tumors in combination with chemotherapy and/ or radiotherapy therapy.Methods 43 cases with soft tissue tumors from 2008 to 2011 were received in our hospital.Basing on X- ray,pathology and histology results,we used different treatment methods.Eleven patients were treated with surgery alone with wide resection;Fourteen patients were treated with preoperative radiotherapy+surgery+postoperative radiotherapy;Nine cases were treated with preoperative cisplatin+surgery+postoperative cisplatin;Nine patients were treated with preoperative radiotherapy+surgery+postop- erative radiotherapy+postoperative eisplatin.Results 7 patients got tumor recurrence ,including one case of plantar fibroma patient. After three times relapse and resection,we took amputation resection.3-year survival rate for all patients was 69.77%,patients with lipoma better survival rate of 100.00%.Conclusion Pre-surgery of X-ray,pathology and histology had significant effects on the choice of treatment for soft tissue tumors.Basing on patient-specific conditions,selecting appropriate treatment can improve clinical efficiency.However,preoperative radiotherapy+surgery+postoperative radiotherapy+postoperative eisplatin can have better clinical effi- ciency for malignant soft tissue tumors.
出处
《中国药业》
CAS
2015年第B11期101-102,共2页
China Pharmaceuticals