摘要
目的：研究影响丙型肝炎感染的危险因素。方法：选取2013年1月~2014年6月期间接受治疗的部分患者1 000例,进行与丙肝感染相关的问卷调查,并采集血样进行抗HCV检测和HCV-RNA含量检测,观察结果为阳性或阴性,阳性结果为感染者,对获得的数据采用SPSS17.0软件进行统计学分析。并采用单因素分析、多因素Logistic回归分析探讨与丙肝感染可能相关因素,采用OR值及其95%置信区间表示危险程度。结果：吸毒史、性伙伴固定与否、供血情况、纹身、输血史、手术史及不安全注射这些因素对于抗-HCV阳性比例均具有统计学意义（P〈0.001）,上述因素的OR值分别为2.253、1.372、10.451、2.589、5.503、1.951、1.672,95%置信区间分别为（1.5204.384）、（1.1642.036）、（6.15219.865）、（1.6825.273）、（3.5239.177）、（1.303-2.731）和（1.1272.563）,这些因素均是对丙型肝炎感染影响相关的独立因素,输血和供血是主要影响因素。结论：吸毒史、供血情况、纹身、输血史、手术史、不安全注射及性伙伴这些因素均为影响丙型肝炎感染相关的独立因素,丙型肝炎预防的重点应为保证血液供应的安全,加强对医院及公共场所的卫生规范管理,增加人们健康生活的宣传教育。
Objective To study the risk factors for hepatitis c infection. Method The 1 000 cases of patients treated in our hospital were selected during the period of January in 2013 to June in 2014, with a questionnaire related to hepatitis c infection, and blood samples were collected for detection of anti HCV and HCV - RNA content detection, the results positive or negative were observed, positive results showed that the patients were infected, the SPSS17.0 software was used to deal with data obtained for statistical analysis, there was statisti- cal significance if P 〈 0. 05. The single factor analysis, multiple factors Logistic regression analysis were used to investigate the factors asso- ciated with HCV infection, the OR and its 95% confidence interval were used to express risk values. Results Drug use, sexual partners fixed or not, the blood supply situation, tattoos, blood transfusion history, history of surgery and unsafe injections of these factors for anti - HCV positive proportion were statistically significant （ P 〈 0. 001 ）, OR of these factors were 2. 253, 1. 372,10. 451,2. 589,5. 503,1. 951, 1. 672, and 95% confidence interval of these factors were （ 1. 520 - 4. 384）, （ 1. 164 - 2. 036 ）, （ 6. 152 - 19. 865 ）, （ 1. 682 - 5. 273 ）, （ 3. 523 - 9. 177 ）, （ 1. 303 - 2.731 ）, （ 1. 127 - 2. 563 ）, these factors were related to the independent factors effect on hepatitis e infection, blood transfusion and blood supplying was the main influence factors. Conclusion Drug use, blood supply, tattoos, history of blood transfusion, surgical history, unsafe injections and sexual partners, these factors are the independent factors affecting hepatitis c infection, focus of hepatitis c prevention should be to ensure the safety of blood supply,it is necessary to strengthen the management of hospitals and public places, and increase propaganda and education of healthy life in people.
出处
《吉林医学》
CAS
2016年第1期87-89,共3页
Jilin Medical Journal
关键词
丙型肝炎
病毒
感染
危险因素
Hepatitis c
Virus
Infection
Risk factors
